Department of Biomedical Engineering, Chonnam National University, 50 Daehak-ro, Yeosu 59626, Korea.
Sensors (Basel). 2019 Dec 19;20(1):33. doi: 10.3390/s20010033.
This study proposes a new structure for a pressure sensor module that can reduce errors caused by measurement position and direction in noninvasive radial artery pulse wave measurement, which is used for physiological monitoring. We have proposed a structure for a multi-array pressure sensor with a hexagonal arrangement and polydimethylsiloxane that easily fits to the structure of the radial artery, and evaluated the characteristics and pulse wave measurement of the developed sensor by finite element method simulation, a push-pull gauge test, and an actual pulse wave measurement experiment. The developed sensor has a measuring area of 17.6 × 17.6 mm and a modular structure with the analog front end embedded on the printed circuit board. The finite element method simulation shows that the developed sensor responds linearly to external pressure. According to the push-pull gauge test results for each channel, there were differences between the channels caused by the unit sensor characteristics and fabrication process. However, the correction formula can minimize the differences and ensure the linearity, and root-mean-squared error is 0.267 kPa in calibrated output. Although additional experiments and considerations on inter-individual differences are required, the results suggested that the proposed multiarray sensor could be used as a radial arterial pulse wave sensor.
本研究提出了一种新的压力传感器模块结构,可减少非侵入性桡动脉脉搏波测量中因测量位置和方向引起的误差,用于生理监测。我们提出了一种具有六角形排列和聚二甲基硅氧烷的多阵列压力传感器结构,该结构易于贴合桡动脉的结构,通过有限元法模拟、推挽式压力计测试和实际脉搏波测量实验评估了所开发传感器的特性和脉搏波测量。所开发的传感器的测量面积为 17.6×17.6mm,采用带有模拟前端的印刷电路板的模块化结构。有限元法模拟表明,所开发的传感器对外压呈线性响应。根据每个通道的推挽式压力计测试结果,由于单元传感器特性和制造工艺的差异,通道之间存在差异。但是,校正公式可以最小化差异并确保线性,在经过校准的输出中,均方根误差为 0.267kPa。尽管需要进行更多的个体差异的实验和考虑,但是研究结果表明,所提出的多阵列传感器可以用作桡动脉脉搏波传感器。