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一种用于精确测量桡动脉脉搏的具有解耦圆形阵列的眼压传感器的研制。

Development of a Tonometric Sensor with a Decoupled Circular Array for Precisely Measuring Radial Artery Pulse.

作者信息

Jun Min-Ho, Kim Young-Min, Bae Jang-Han, Jung Chang Jin, Cho Jung-Hee, Jeon Young Ju

机构信息

KM Fundamental Research Division, Korea Institute of Oriental Medicine (KIOM), Daejeon 305-811, Korea.

出版信息

Sensors (Basel). 2016 May 26;16(6):768. doi: 10.3390/s16060768.

Abstract

The radial artery pulse is one of the major diagnostic indices used clinically in both Eastern and Western medicine. One of the prominent methods for measuring the radial artery pulse is the piezoresistive sensor array. Independence among channels and an appropriate sensor arrangement are important for effectively assessing the spatial-temporal information of the pulse. This study developed a circular-type seven-channel piezoresistive sensor array using face-down bonding (FDB) as one of the sensor combination methods. The three-layered housing structure that included independent pressure sensor units using the FDB method not only enabled elimination of the crosstalk among channels, but also allowed various array patterns to be created for effective pulse measurement. The sensors were arranged in a circular-type arrangement such that they could estimate the direction of the radial artery and precisely measure the pulse wave. The performance of the fabricated sensor array was validated by evaluating the sensor sensitivity per channel, and the possibility of estimating the blood vessel direction was demonstrated through a radial artery pulse simulator. We expect the proposed sensor to allow accurate extraction of the pulse indices for pulse diagnosis.

摘要

桡动脉脉搏是东西方医学临床使用的主要诊断指标之一。测量桡动脉脉搏的一种突出方法是压阻式传感器阵列。通道之间的独立性和适当的传感器布置对于有效评估脉搏的时空信息很重要。本研究开发了一种采用倒装芯片键合(FDB)作为传感器组合方法之一的圆形七通道压阻式传感器阵列。使用FDB方法的包括独立压力传感器单元的三层外壳结构不仅能够消除通道间的串扰,还允许创建各种阵列模式以进行有效的脉搏测量。传感器以圆形排列,以便能够估计桡动脉的方向并精确测量脉搏波。通过评估每个通道的传感器灵敏度来验证所制造传感器阵列的性能,并通过桡动脉脉搏模拟器证明估计血管方向的可能性。我们期望所提出的传感器能够准确提取用于脉搏诊断的脉搏指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f93f/4934194/f43f4113f132/sensors-16-00768-g001.jpg

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