镰状细胞贫血（SS）和镰状细胞特性（SC）血红蛋白病的眼底改变。对巴西人群的研究。

Funduscopic alterations in SS and SC hemoglobinopathies. Study of a Brazilian population.

作者信息

Bonanomi M T, Cunha S L, de Araújo J T

机构信息

Department of Ophthalmology, São Paulo University Medical School, Brazil.

出版信息

Ophthalmologica. 1988;197(1):26-33. doi: 10.1159/000309913.

DOI:10.1159/000309913

PMID:3186205

Abstract

Fundus changes in sickle cell disease are well studied and documented according to their clinical and angiographic aspects. Sickle cell retinopathy was studied in a Brazilian population of 63 patients (41 with SS hemoglobinopathy, and 22 with SC hemoglobinopathy). All ophthalmoscopic changes observed in our patients were more frequent in the SC group with the exception of atrophic retinal tears, found only in the SS group. Proliferative retinopathy including its complications was seen in 54.54% of the eyes of the SC group, and in only 14.64% of the eyes of the SS group. Decreased vision is consequently greater in the SC group. Despite the great frequency of funduscopic changes in both groups, only 1 patient suffered irreversible visual loss due to retinal detachment operated on without success.

摘要

镰状细胞病的眼底变化已根据其临床和血管造影方面进行了充分研究和记录。对巴西63名患者（41名患有SS血红蛋白病，22名患有SC血红蛋白病）的镰状细胞视网膜病变进行了研究。我们的患者中观察到的所有眼底镜变化在SC组中更为常见，但萎缩性视网膜裂孔仅在SS组中发现。增殖性视网膜病变及其并发症在SC组的54.54%的眼中可见，而在SS组的眼中仅为14.64%。因此，SC组的视力下降更为严重。尽管两组眼底镜变化的发生率都很高，但只有1名患者因视网膜脱离手术失败而遭受不可逆的视力丧失。