Hohenauer L, Eidenberger G, Eitelberger F, Tulzer G
Neugeborenen-und Säuglingsabteilung des Landes-Kinderkrankenhauses Linz.
Padiatr Padol. 1988;23(3):177-84.
Among 829 consecutively treated neonatal intensive care patients during the years 1985 and 1986 46 cases of early onset type an 14 cases of late onset type (beyond the 4th day of life) of sepsis neonatorum were diagnosed. Mortality was 20%. In 40% of the cultures penicillin-resistant staphylococcus epidermidis was found. It was resistant to Penicillin however fully sensitive to Cefamandol, Netilmycine and Amicacine. Primary therapy of early onset type of sepsis has to be effective against Streptococci and against Listeria monocytogenes. Blood culture is the only way to proove or to exclude sepsis at a rational way. Good hospital hygiene can prevent a part of late onset type of sepsis. Immuntherapy is regarded as an import part of Sepsistherapy in the newborn.
在1985年和1986年连续接受治疗的829例新生儿重症监护患者中，诊断出46例早发型和14例晚发型（出生后第4天以后）新生儿败血症。死亡率为20%。在40%的培养物中发现了耐青霉素表皮葡萄球菌。它对青霉素耐药，但对头孢孟多、奈替米星和阿米卡星完全敏感。早发型败血症的初始治疗必须对链球菌和单核细胞增生李斯特菌有效。血培养是合理证实或排除败血症的唯一方法。良好的医院卫生状况可以预防部分晚发型败血症。免疫疗法被视为新生儿败血症治疗的重要组成部分。
