经耳迷走神经刺激在一组意识障碍患者中的可行性、安全性和有效性。 - Suppr

Feasibility, safety and efficacy of transauricular vagus nerve stimulation in a cohort of patients with disorders of consciousness.

作者信息

Noé Enrique, Ferri Joan, Colomer Carolina, Moliner Belén, O'Valle Myrtha, Ugart Patricia, Rodriguez Clara, Llorens Roberto

机构信息

NEURORHB. Servicio De Neurorrehabilitación de Hospitales Vithas, València, Spain; Fundación Salud y Cerebro, València, Spain; Fundación Hospitales Vithas, València, Spain.

出版信息

Brain Stimul. 2020 Mar-Apr;13(2):427-429. doi: 10.1016/j.brs.2019.12.005. Epub 2019 Dec 12.

DOI:10.1016/j.brs.2019.12.005

PMID:31866491

Abstract

摘要

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Feasibility, safety and efficacy of transauricular vagus nerve stimulation in a cohort of patients with disorders of consciousness.经耳迷走神经刺激在一组意识障碍患者中的可行性、安全性和有效性。

Brain Stimul. 2020 Mar-Apr;13(2):427-429. doi: 10.1016/j.brs.2019.12.005. Epub 2019 Dec 12.

Transauricular vagus nerve stimulation for patients with disorders of consciousness: A randomized controlled clinical trial.经耳迷走神经刺激治疗意识障碍患者：一项随机对照临床试验。

Front Neurol. 2023 Mar 2;14:1133893. doi: 10.3389/fneur.2023.1133893. eCollection 2023.

Stimulation of vagus nerve for patients with disorders of consciousness: a systematic review.迷走神经刺激治疗意识障碍患者：一项系统综述。

Front Neurosci. 2023 Sep 15;17:1257378. doi: 10.3389/fnins.2023.1257378. eCollection 2023.

Measures of metabolism and complexity in the brain of patients with disorders of consciousness.意识障碍患者大脑中的代谢与复杂性测量

Neuroimage Clin. 2017 Feb 6;14:354-362. doi: 10.1016/j.nicl.2017.02.002. eCollection 2017.

Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients.内源性功能连接可区分最小意识和无反应患者。

Brain. 2015 Sep;138(Pt 9):2619-31. doi: 10.1093/brain/awv169. Epub 2015 Jun 27.

Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study.从最小意识状态中恢复过来的患者的意识神经相关因素：一项横断面多模态成像研究。

Lancet Neurol. 2016 Jul;15(8):830-842. doi: 10.1016/S1474-4422(16)00111-3. Epub 2016 Apr 27.

Disorders of consciousness after severe traumatic brain injury: a Swedish-Icelandic study of incidence, outcomes and implications for optimizing care pathways.严重创伤性脑损伤后的意识障碍：一项瑞典-冰岛研究，探讨其发生率、结局及对优化护理路径的影响。

J Rehabil Med. 2013 Sep;45(8):741-8. doi: 10.2340/16501977-1167.

Results of a prospective study (CATS) on the effects of thalamic stimulation in minimally conscious and vegetative state patients.前瞻性研究（CATS）关于丘脑刺激对最小意识状态和植物状态患者影响的结果。

J Neurosurg. 2016 Oct;125(4):972-981. doi: 10.3171/2015.7.JNS15700. Epub 2016 Jan 8.

Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: a clinical validation study.正电子发射断层扫描成像和功能磁共振成像在意识障碍中的诊断精度：一项临床验证研究。

Lancet. 2014 Aug 9;384(9942):514-22. doi: 10.1016/S0140-6736(14)60042-8. Epub 2014 Apr 15.

Transcranial direct current stimulation effects in disorders of consciousness.经颅直流电刺激治疗意识障碍的效果。

Arch Phys Med Rehabil. 2014 Feb;95(2):283-9. doi: 10.1016/j.apmr.2013.09.002. Epub 2013 Sep 11.

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Electroencephalographic characteristics of transcutaneous auricular vagus nerve stimulation for prolonged disorders of consciousness: a study protocol.经皮耳迷走神经刺激治疗长期意识障碍的脑电图特征：一项研究方案

Front Neurosci. 2025 May 6;19:1539232. doi: 10.3389/fnins.2025.1539232. eCollection 2025.

Effects of transcutaneous auricular vagus nerve stimulation on postoperative delirium in older patients with hip fracture: protocol for a randomised controlled trial.经皮耳迷走神经刺激对老年髋部骨折患者术后谵妄的影响：一项随机对照试验方案

BMJ Open. 2025 Feb 20;15(2):e092413. doi: 10.1136/bmjopen-2024-092413.

Case report: Monitoring consciousness with fNIRS in a patient with prolonged reduced consciousness following hemorrhagic stroke undergoing adjunct taVNS therapy.病例报告：在一名出血性中风后意识长期减退并接受辅助经皮迷走神经刺激（taVNS）治疗的患者中，使用功能近红外光谱（fNIRS）监测意识。

Front Neurosci. 2025 Feb 4;19:1519939. doi: 10.3389/fnins.2025.1519939. eCollection 2025.

Vagus nerve stimulation: a physical therapy with promising potential for central nervous system disorders.迷走神经刺激：一种对中枢神经系统疾病具有潜在前景的物理治疗方法。

Front Neurol. 2024 Dec 13;15:1516242. doi: 10.3389/fneur.2024.1516242. eCollection 2024.

The efficacy and safety of bilateral synchronous transcutaneous auricular vagus nerve stimulation for prolonged disorders of consciousness: a multicenter, double-blind, stratified, randomized controlled trial protocol.双侧同步经皮耳迷走神经刺激治疗长期意识障碍的疗效和安全性：一项多中心、双盲、分层、随机对照试验方案

Front Neurol. 2024 May 31;15:1418937. doi: 10.3389/fneur.2024.1418937. eCollection 2024.

Transcutaneous auricular vagal nerve stimulation for consciousness recovery in patients with prolonged disorders of consciousness (TAVREC): study protocol for a multicenter, triple-blind, randomized controlled trial in China.经皮耳迷走神经刺激治疗意识障碍患者意识恢复的多中心、三盲、随机对照试验（TAVREC）：在中国进行的研究方案。

BMJ Open. 2024 May 31;14(5):e083888. doi: 10.1136/bmjopen-2024-083888.

An update on noninvasive neuromodulation in the treatment of patients with prolonged disorders of consciousness.关于非侵入性神经调节治疗意识障碍延长患者的最新进展。

CNS Neurosci Ther. 2024 May;30(5):e14757. doi: 10.1111/cns.14757.

Minimally conscious state plus versus minus: Likelihood of emergence and long-term functional independence.最小意识状态阳性与阴性：觉醒的可能性和长期功能独立性。

Ann Clin Transl Neurol. 2024 Mar;11(3):719-728. doi: 10.1002/acn3.51993. Epub 2024 Feb 17.

Current status and prospect of transcutaneous auricular vagus nerve stimulation for disorders of consciousness.经皮耳迷走神经刺激治疗意识障碍的现状与展望

Front Neurosci. 2024 Jan 8;17:1274432. doi: 10.3389/fnins.2023.1274432. eCollection 2023.

The efficacy and safety of transcutaneous auricular vagus nerve stimulation for patients with minimally conscious state: a sham-controlled randomized double-blind clinical trial.经皮耳迷走神经刺激对最低意识状态患者的疗效与安全性：一项假刺激对照的随机双盲临床试验

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Feasibility, safety and efficacy of transauricular vagus nerve stimulation in a cohort of patients with disorders of consciousness.

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