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败血梭状芽孢杆菌性主动脉炎:与魔鬼的亲吻。

Clostridium septicum aortitis: A kiss of the devil.

作者信息

Ranchal Purva, Ferin Adam, Gupta Rahul, Malekan Ramin, Goldberg Joshua, Laskowski Igor, El Khoury Marc Y

机构信息

Department of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York.

Department of Infectious Diseases, Westchester Medical Center, New York Medical College, Valhalla, New York.

出版信息

J Card Surg. 2020 Feb;35(2):514-517. doi: 10.1111/jocs.14402. Epub 2019 Dec 24.

DOI:10.1111/jocs.14402
PMID:31872897
Abstract

BACKGROUND

Clostridium septicum aortitis is a lethal infection. C. septicum has a strong association with an underlying malignancy, most commonly in the colon.

AIM

Early identification methods and management strategies of C. Septicum infection.

MATERIALS AND METHODS

We present a 64-year-old man with aortic aneurysm and C. septicum bacteremia with unknown malignancy who passed away on the fourth day of hospitalization despite emergent endovascular intervention. Computed tomography showed periaortic gas which is the hallmark of infection.

DISCUSSION

This case report highlights the need of prompt surgical treatment and its different modalities along with the early use of appropriate antibiotics due to the rapid spread of infection associated with high fatality. The authors also discuss the association of C. septicum aortitis with underlying occult malignancies.

CONCLUSION

Delay in identification and treatment of C. Septicum is associated with very high mortality rates.

摘要

背景

败血梭菌性主动脉炎是一种致命感染。败血梭菌与潜在恶性肿瘤密切相关,最常见于结肠。

目的

败血梭菌感染的早期识别方法及管理策略。

材料与方法

我们报告一名64岁患有主动脉瘤和败血梭菌菌血症且伴有不明恶性肿瘤的男性患者,尽管进行了紧急血管内介入治疗,但仍在住院第四天去世。计算机断层扫描显示主动脉周围气体,这是感染的标志。

讨论

本病例报告强调了由于感染迅速传播且死亡率高,需要及时进行手术治疗及其不同方式,同时早期使用适当抗生素。作者还讨论了败血梭菌性主动脉炎与潜在隐匿性恶性肿瘤的关联。

结论

败血梭菌的识别和治疗延迟与极高的死亡率相关。

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