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[吲哚菁绿(ICG)在进展期胃癌腹腔镜导航手术中的应用进展与争议]

[Progress and controversy of indocyanine green (ICG) used in laparoscopic navigation surgery for advanced gastric cancer].

作者信息

Tian Y T, Ma S

机构信息

Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

出版信息

Zhonghua Zhong Liu Za Zhi. 2019 Dec 23;41(12):896-899. doi: 10.3760/cma.j.issn.0253-3766.2019.12.003.

DOI:10.3760/cma.j.issn.0253-3766.2019.12.003
PMID:31874545
Abstract

Indocyanine green (ICG) has been used as a novel tracer for mapping lymph nodes in navigation surgeries for many malignant tumors. Recently, ICG is mainly applied in sentinel lymph node biopsy for early gastric cancer, while its application in advanced gastric cancer is less reported. It was reported that application of ICG in locating perigastric lymph nodes could elevate the efficiency of lymphadenectomy for advanced gastric cancer. Besides, recognizing small lymph nodes and dissecting certain lymph node stations are its unique advantages. However, some problems remain unsolved, as few relevant research has been done. Based on conceptions of minimal invasive and precision medicine, ICG may play an important role in improving the accuracy of laparoscopic surgery for advanced gastric cancer in the future.

摘要

吲哚菁绿(ICG)已被用作许多恶性肿瘤导航手术中淋巴结定位的新型示踪剂。最近,ICG主要应用于早期胃癌的前哨淋巴结活检,而其在进展期胃癌中的应用报道较少。据报道,ICG在定位胃周淋巴结方面的应用可提高进展期胃癌淋巴结清扫的效率。此外,识别小淋巴结和解剖特定淋巴结站是其独特优势。然而,由于相关研究较少,一些问题仍未解决。基于微创和精准医学的理念,ICG未来可能在提高进展期胃癌腹腔镜手术的准确性方面发挥重要作用。

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