Ren Xiang-Fang, Wang Zi-Zhen, Yang Mei, Li Lei, Kong Xiang-Yong, Feng Zhi-Chun
Bayi Children's Hospital, Seventh Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing 100700, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2019 Dec;21(12):1159-1163. doi: 10.7499/j.issn.1008-8830.2019.12.002.
To study the clinical effect of white noise combined with glucose in reducing the procedural pain of retinopathy screening in preterm infants.
A total of 396 preterm infants with a gestational age of 28-34 weeks and a birth weight of ≤2 000 g were randomly divided into 4 groups according to the intervention method for reducing pain in retinopathy screening: control group with 100 infants (no white noise or glucose intervention), white noise group with 96 infants, glucose group with 98 infants and white noise + glucose group with 102 infants. The Premature Infant Pain Profile (PIPP) was used to determine pain score during retinopathy screening, and the four groups were compared in terms of PIPP score before and after retinopathy screening.
There were no significant differences in PIPP score, heart rate and blood oxygen saturation between the four groups at 3 minutes before screening (P>0.05). At 1 and 5 minutes after screening, the white noise, glucose and white noise + glucose groups had significantly lower heart rate and PIPP score but significantly higher blood oxygen saturation than the control group (P<0.05).The white noise + glucose group had significantly lower heart rate and PIPP score but significantly higher blood oxygen saturation than the white noise and glucose groups (P<0.05).
White noise combined with glucose can reduce the procedural pain of retionopathy screening and keep vital signs stable in preterm infants.
探讨白噪音联合葡萄糖在减轻早产儿视网膜病变筛查过程中疼痛的临床效果。
选取396例孕周为28 - 34周、出生体重≤2000g的早产儿,根据减轻视网膜病变筛查疼痛的干预方法随机分为4组:对照组100例(无白噪音及葡萄糖干预),白噪音组96例,葡萄糖组98例,白噪音 + 葡萄糖组102例。采用早产儿疼痛量表(PIPP)评估视网膜病变筛查过程中的疼痛评分,比较4组患儿视网膜病变筛查前后的PIPP评分。
筛查前3分钟,4组患儿的PIPP评分、心率及血氧饱和度比较,差异无统计学意义(P>0.05)。筛查后1分钟及5分钟,白噪音组、葡萄糖组、白噪音 + 葡萄糖组的心率及PIPP评分均显著低于对照组,血氧饱和度显著高于对照组(P<0.05)。白噪音 + 葡萄糖组的心率及PIPP评分显著低于白噪音组和葡萄糖组,血氧饱和度显著高于白噪音组和葡萄糖组(P<0.05)。
白噪音联合葡萄糖可减轻早产儿视网膜病变筛查过程中的疼痛,并维持生命体征稳定。