Forrester J E, Scott M E, Bundy D A, Golden M H
Institute of Parasitology, Macdonald College of McGill University, Ste-Anne de Bellevue, Quebec, Canada.
Trans R Soc Trop Med Hyg. 1988;82(2):282-8. doi: 10.1016/0035-9203(88)90448-8.
A survey of 428 households in a shanty town in Coatzacoalcos, Mexico, revealed high prevalences of Ascaris lumbricoides and Trichuris trichiura. The data were analysed separately for A. lumbricoides and T. trichiura in order to investigate the spatial distribution of heavy infections through the town. Within each age class, those individuals with egg counts in the upper 20% of the range for that age were classified as "heavily infected". When the data were stratified by household size, it was found that the distribution of "heavily-infected" individuals was not random in the community. "Heavily-infected" individuals were found together in households; fewer household units had a single heavily-infected individual than would be expected by chance. Such a pattern could result either from genetic similarities among family members influencing their ability to mount an effective immunological response to infection, or focal transmission in the vicinity of the home, or both. This result may have important implications for the development of community control programmes.
对墨西哥科阿特萨科科斯一个棚户区的428户家庭进行的一项调查显示，蛔虫和鞭虫的感染率很高。为了调查整个城镇重度感染的空间分布情况，分别对蛔虫和鞭虫的数据进行了分析。在每个年龄组中，那些虫卵计数处于该年龄范围前20%的个体被归类为“重度感染”。当数据按家庭规模分层时，发现“重度感染”个体在社区中的分布并非随机。“重度感染”个体在家庭中聚集在一起；单个家庭中出现单个重度感染个体的家庭单位比随机预期的要少。这种模式可能是由于家庭成员之间的基因相似性影响了他们对感染产生有效免疫反应的能力，或者是由于家庭附近的局部传播，或者两者兼而有之。这一结果可能对社区控制项目的开展具有重要意义。
