使用新型便携式近红外光谱仪确定足月儿局部脑组织氧饱和度的参考范围。

Defining the reference range of regional cerebral tissue oxygen saturation using a new portable near-infrared spectroscopy device for term infants.

作者信息

Ozawa Junichi, Watanabe Takaaki, Ito Masato, Miyake Fuyu, Nagano Nobuhiko, Ogawa Ryo, Matsumura Shun, Araki Ryuichiro, Tamura Masanori, Namba Fumihiko

机构信息

Department of Pediatrics, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe, Saitama 350-8550, Japan.

Community Health Science Center, Saitama Medical University, 38 Morohongo, Moroyama, Iruma, Saitama 350-0495, Japan.

出版信息

Early Hum Dev. 2020 Feb;141:104941. doi: 10.1016/j.earlhumdev.2019.104941. Epub 2019 Dec 25.

DOI:10.1016/j.earlhumdev.2019.104941

PMID:31883487

Abstract

BACKGROUND

The arterial oxygen saturation of infants requiring resuscitation can be monitored using a pulse oximeter. However, the device cannot provide information about cerebral oxygenation. Thus, we used a new portable near-infrared spectroscopy (NIRS) device that can monitor regional cerebral tissue oxygen saturation (crSO) with a probe attached to the examiner's finger.

AIM

To identify the reference ranges for crSO within the first 10 min after birth in term infants who did not receive any medical intervention in the delivery room.

RESULTS

crSO in the left frontoparietal area of the forebrain was measured within the first 10 min of life in 127 healthy term infants. The median gestational age and birth weight were 37.6 weeks and 2742 g, respectively, and 85% of the infants were delivered via a scheduled cesarean section. The 3rd-97th percentile values for crSO ranged from 33.1% to 56.7% at 1 min, from 33.2% to 59.5% at 2 min, and from 38.7% to 66.6% at 5 min after birth. A median of 3.5 min was required to achieve a crSO > 50%.

CONCLUSIONS

This study showed the reference ranges for crSO measured with the new portable NIRS device within the first 10 min after birth in term infants.

摘要

背景

需要复苏的婴儿的动脉血氧饱和度可用脉搏血氧仪进行监测。然而，该设备无法提供有关脑氧合的信息。因此，我们使用了一种新型便携式近红外光谱（NIRS）设备，该设备可通过连接在检查者手指上的探头监测局部脑组织氧饱和度（crSO）。

目的

确定出生后10分钟内未在产房接受任何医学干预的足月儿的crSO参考范围。

结果

对127名健康足月儿在出生后10分钟内测量了前脑左额顶叶区域的crSO。中位胎龄和出生体重分别为37.6周和2742克，85%的婴儿通过择期剖宫产分娩。出生后1分钟时crSO的第3-97百分位数范围为33.1%至56.7%，2分钟时为33.2%至59.5%，5分钟时为38.7%至66.6%。达到crSO>50%的中位时间为3.5分钟。