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剖宫产术中不同麻醉方法对新生儿脑和肾氧合作用影响的比较:一项随机对照试验

Comparison of the Effects of Anaesthesia Methods Used in Caesarean Delivery on Neonatal Cerebral and Renal Oxygenation: A Randomised Controlled Trial.

作者信息

Arslan Ulku, Kavrut Ozturk Nilgun, Kavakli Ali Sait, Dagdelen Hatice Ozge

机构信息

Department of Anesthesiology and Reanimation, University of Health Sciences, Antalya Training and Research Hospital, 07100 Antalya, Turkey.

Department of Anesthesiology and Reanimation, Istinye University Faculty of Medicine, 34010 Istanbul, Turkey.

出版信息

J Clin Med. 2024 Feb 2;13(3):873. doi: 10.3390/jcm13030873.

Abstract

: During a newborn's adaptation to extrauterine life, many changes take place that are influenced by various factors. The type of delivery and anaesthesia strategy utilised during labour can modify these adaptive modifications. In this regard, this study was designed to compare the effects of general and spinal anaesthesia on cerebral and renal oxygenation after elective caesarean deliveries. : This randomised controlled study comprised sixty parturient women who were over 18 years old and had a gestational age between 37 and 41 weeks. All participants had an ASA (American Society of Anesthesiologists) classification of II. Neonatal cerebral (CrSO) and renal (RrSO) regional oxygen saturations were assessed using near-infrared spectroscopy. Additionally, the 1st-5th min Apgar scores, preductal and postductal peripheral oxygen saturation (SpO), and perfusion index were recorded in both the general anaesthesia and spinal anaesthesia groups. : There was no statistically significant difference between the two groups in terms of CrSO or RrSO values. The values of CrSO and RrSO in both groups showed a significant rise from the 10th to the 15th min, respectively. : General and spinal anaesthesia techniques used for cesarean delivery have similar effects on neonatal cerebral and renal oxygenation.

摘要

在新生儿适应宫外生活的过程中,会发生许多受各种因素影响的变化。分娩期间采用的分娩方式和麻醉策略可改变这些适应性变化。在这方面,本研究旨在比较全身麻醉和脊髓麻醉对择期剖宫产术后脑和肾氧合的影响。

这项随机对照研究包括60名年龄超过18岁、孕周在37至41周之间的产妇。所有参与者的美国麻醉医师协会(ASA)分级均为II级。使用近红外光谱法评估新生儿脑(CrSO)和肾(RrSO)区域氧饱和度。此外,记录全身麻醉组和脊髓麻醉组第1至5分钟的阿氏评分、导管前和导管后外周血氧饱和度(SpO)以及灌注指数。

两组之间的CrSO或RrSO值无统计学显著差异。两组的CrSO和RrSO值分别在第10至15分钟有显著升高。

剖宫产所用的全身麻醉和脊髓麻醉技术对新生儿脑和肾氧合有相似的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3abd/10856314/3252460e0090/jcm-13-00873-g001.jpg

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