Fernandes Natália Coelho Couto de Azevedo, do Nascimento Paloma Martins, Sánchez-Sarmiento Angélica M, Ressio Rodrigo A, Dos Santos Cirqueira Cinthya, Kanamura Cristina Takami, de Carvalho Júlia, da Silva Silvana Mello Pereira, Peruchi Amanda Rezende, de Souza Junior Julio César, Hirano Zelinda Maria Braga, Catão-Dias José Luiz
Centro de Patologia, Instituto Adolfo Lutz, São Paulo, Brazil.
Laboratório de Patologia Comparada de Animais Selvagens, Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
J Med Primatol. 2020 Apr;49(2):65-70. doi: 10.1111/jmp.12456. Epub 2019 Dec 30.
Non-human primates (NHPs) are susceptible to dogs' attacks, events that may cause muscle damage along with stress, and could be in some extent compatible with capture myopathy, a syndrome that results in myoglobinuria and renal damage.
We aimed to evaluate by histopathology pre-existing lesions and subsequent sequelae related to dogs' attacks, acute tubular necrosis (ATN) and myoglobinuria, as well as the usefulness of Pearls Stain and IHC to diagnose it. Histopathology was performed in available organs, and sections of kidney submitted to Prussian blue stain and myoglobin immunohistochemistry.
During January 2014-June 2016, 16/145 (11%) of NHPs received by Adolfo Lutz Institute, Brazil were reported as attacked by dogs. A high frequency of young and debilitated animals was found. Myoglobinuria was observed in more than half animals (9/16; 56.2%), from which (5/9; 55.5%) presented ATN.
Kidney lesions are plausible findings in NHPs attacked by dogs.
