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以急性呼吸窘迫综合征为首发表现且需要体外膜肺氧合支持的抗中性粒细胞胞浆自身抗体阳性血管炎

Acute Respiratory Distress Syndrome Requiring Extracorporeal Membrane Oxygenation as the Initial Presentation of Anti-neutrophillic Cytoplasmic Auto-antibody Positive Vasculitis.

作者信息

Kundu Suhali, Sharma Shaurya, Minhas Ramandeep, Scheers-Masters Joshua, Saunders Paul C

机构信息

Internal Medicine, Maimonides Medical Center, Brooklyn, USA.

Diagnostic Radiology, SUNY Downstate Medical Center, Brooklyn, USA.

出版信息

Cureus. 2019 Nov 12;11(11):e6135. doi: 10.7759/cureus.6135.

DOI:10.7759/cureus.6135
PMID:31886071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6903887/
Abstract

Acute respiratory distress syndrome (ARDS) is a life-threatening inflammatory state of lung injury that can require acute interventions including mechanical ventilation as well as emergent veno-venous extracorporeal membrane oxygenation (VV-ECMO) for management. Etiologies of ARDS are not clearly discernible in certain cases and can vary from sepsis, pneumonia, trauma and intoxication. Anti-nuclear cytoplasmic auto-antibody (ANCA)-associated vasculitis (AAV) is a group of several conditions that can have pulmonary complications including ARDS. We present a case where the primary manifestation of myeloperoxidase (MPO)-ANCA positive vasculitis was ARDS, in order to highlight the importance of investigating rare vasculitides as the underlying cause of ARDS and the importance of ECMO as an early life-saving intervention for the management of ARDS.

摘要

急性呼吸窘迫综合征（ARDS）是一种危及生命的肺损伤炎症状态，可能需要包括机械通气以及紧急静脉 - 静脉体外膜肺氧合（VV - ECMO）在内的急性干预措施来进行治疗。在某些情况下，ARDS的病因并不明确，可能包括败血症、肺炎、创伤和中毒等。抗中性粒细胞胞浆自身抗体（ANCA）相关血管炎（AAV）是一组可能出现包括ARDS在内的肺部并发症的疾病。我们报告了一例以髓过氧化物酶（MPO） - ANCA阳性血管炎为主要表现的ARDS病例，以强调将罕见血管炎作为ARDS潜在病因进行调查的重要性，以及ECMO作为ARDS早期挽救生命干预措施的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/ab0e9d799873/cureus-0011-00000006135-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/c1a7a2f8889a/cureus-0011-00000006135-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/4c96c46c1ddd/cureus-0011-00000006135-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/0224705b7ec7/cureus-0011-00000006135-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/ab0e9d799873/cureus-0011-00000006135-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/c1a7a2f8889a/cureus-0011-00000006135-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/4c96c46c1ddd/cureus-0011-00000006135-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/0224705b7ec7/cureus-0011-00000006135-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e27/6903887/ab0e9d799873/cureus-0011-00000006135-i04.jpg

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