Uranova N A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(7):52-8.
Samples of the prefrontal cortex neuropile autopsied from schizophrenic patients were subjected to electron microscopy. Dystrophic changes were found in the dendrites: pronounced swelling with microtubuli reduced in number or totally absent and mitochondria swollen. Synaptic changes were generally of a functional nature but presynaptic endings were found degenerating with a dense type. Myelinated fibers of various diameters showed pathologic changes. These findings are seen as a structural background for integrative and informative processes deterioration in the prefrontal cortex of schizophrenic patients.
对精神分裂症患者尸检获得的前额叶皮质神经纤维网样本进行电子显微镜检查。发现树突有营养不良性改变：明显肿胀，微管数量减少或完全缺失，线粒体肿胀。突触变化一般具有功能性，但发现突触前终末呈致密型退变。不同直径的有髓纤维显示出病理变化。这些发现被视为精神分裂症患者前额叶皮质整合和信息处理过程恶化的结构基础。
