Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
Cancer Screening Center, National Cancer Center Hospital, Tokyo, Japan.
Gut Liver. 2020 Nov 15;14(6):673-684. doi: 10.5009/gnl19266.
This systematic review aimed to assess the efficacy of the current approach to tissue traction during the endoscopic submucosal dissection (ESD) of superficial esophageal cancer, early gastric cancer, and colorectal neoplasms. We performed a systematic electronic literature search of articles published in PubMed and selected comparative studies to investigate the treatment outcomes of tractionassisted versus conventional ESD. Using the keywords, we retrieved 381 articles, including five eligible articles on the esophagus, 13 on the stomach, and 12 on the colorectum. A total of seven randomized controlled trials and 23 retrospective studies were identified. Clip line traction and submucosal tunneling were effective in reducing the procedural time during esophageal ESD. The efficacy of traction methods in gastric ESD varied in terms of the devices and strategies used depending on the lesion location and degree of submucosal fibrosis. Several prospective and retrospective studies utilized traction devices without the need to reinsert the colonoscope. When pocket creation is included, the traction devices and methods effectively shorten the procedural time during colorectal ESD. Although the efficacy is dependent on the organ and tumor locations, several traction techniques have been demonstrated to be efficacious in facilitating ESD by maintaining satisfactory traction during dissection.
本系统评价旨在评估当前在浅表食管癌、早期胃癌和结直肠肿瘤内镜黏膜下剥离(ESD)过程中组织牵引的疗效。我们对 PubMed 上发表的文章进行了系统的电子文献检索,并选择了比较研究来调查牵引辅助与传统 ESD 的治疗效果。使用关键词,我们检索到 381 篇文章,其中包括 5 篇关于食管的、13 篇关于胃的和 12 篇关于结直肠的。共确定了 7 项随机对照试验和 23 项回顾性研究。夹线牵引和黏膜下隧道形成在减少食管 ESD 过程中的手术时间方面是有效的。在胃 ESD 中,根据病变位置和黏膜下纤维化程度,牵引方法的效果因所使用的器械和策略而异。一些前瞻性和回顾性研究使用了不需要重新插入结肠镜的牵引器械。当包括口袋形成时,牵引器械和方法通过在解剖过程中保持满意的牵引力,有效地缩短了结直肠 ESD 的手术时间。尽管疗效取决于器官和肿瘤位置,但已经证明了几种牵引技术在促进 ESD 方面是有效的,因为它们可以在解剖过程中保持满意的牵引力。