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现代24小时社会对2型糖尿病发展的影响:睡眠不足的作用。

The contribution of modern 24-hour society to the development of type 2 diabetes mellitus: the role of insufficient sleep.

作者信息

Karthikeyan Ramanujam, Spence David Warren, Pandi-Perumal Seithikurippu R

机构信息

Madurai Kamaraj Univesity, Dept. of Animal Behavior & Physiology, School of Biological Sciences, - Madurai - 625021, Tamil Nadu - India.

Independent Researcher, Department of Sleep Medicine - Toronto - Ontario - Canada.

出版信息

Sleep Sci. 2019 Jul-Sep;12(3):227-231. doi: 10.5935/1984-0063.20190061.

Abstract

Epidemiological studies since 1980 have shown significant increases in the incidence of type 2 diabetes mellitus (T2DM). The public health burden generated by the growing prevalence of T2DM, which, in its fully developed form, is a lifelong illness, has been associated with further social and economic costs in affected countries. Recent studies have suggested that chronic sleep insufficiency or disrupted or poor quality sleep could contribute to the development of T2DM. Although many research findings have now shown that sleep plays a key role in glucose metabolism, the full implications of these findings have not been translated into clinical programs for improving patients' sleep quality as a means for addressing the treatment of T2DM. The purpose of this brief overview is to focus on the clinical significance of sleep in the onset and treatment of T2DM. We suggest here that physician education should emphasize the importance of sufficient sleep for overall health, including the management of T2DM, and that steps should be taken to incorporate this perspective into clinical practice. The promotion of sleep hygiene techniques as a clinical intervention could improve the regulation of glucose metabolism and thus the longevity of T2DM patients. Moreover, it may prevent secondary complications accruing from the illness and consequently reduce the significant medical costs of treating T2DM patients.

摘要

自1980年以来的流行病学研究表明,2型糖尿病(T2DM)的发病率显著上升。T2DM患病率不断增加所产生的公共卫生负担,这种疾病在其完全发展的形式下是一种终身疾病,与受影响国家的进一步社会和经济成本相关。最近的研究表明,慢性睡眠不足或睡眠中断或质量差可能导致T2DM的发生。尽管现在许多研究结果表明睡眠在葡萄糖代谢中起关键作用,但这些发现的全部意义尚未转化为改善患者睡眠质量的临床方案,以此作为治疗T2DM的一种手段。本简要概述的目的是关注睡眠在T2DM发病和治疗中的临床意义。我们在此建议,医生教育应强调充足睡眠对整体健康的重要性,包括对T2DM的管理,并且应采取措施将这一观点纳入临床实践。推广睡眠卫生技术作为一种临床干预措施,可以改善葡萄糖代谢的调节,从而延长T2DM患者的寿命。此外,它可能预防该疾病产生的继发性并发症,从而降低治疗T2DM患者的巨额医疗成本。

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The Epidemiology of Sleep and Diabetes.睡眠与糖尿病的流行病学。
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