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一名胃腺癌播散至腹膜后间隙患者姑息性放疗后的远隔效应:来自拉丁美洲参考中心的病例报告及文献综述

Abscopal Effect After Palliative Radiotherapy in a Patient with a Gastric Adenocarcinoma Disseminated to Retroperitoneal Space: Case Report from a Latin American Reference Center and Review of the Literature.

作者信息

Bonilla Carlos E, Esguerra José, Mendoza Díaz Sara, Álvarez Angelina, Morales R Laura

机构信息

Oncology, Instituto Nacional de Cancerologia, Bogota, COL.

Radiation Oncology, Instituto Nacional de Cancerologia, Bogota, COL.

出版信息

Cureus. 2019 Nov 26;11(11):e6235. doi: 10.7759/cureus.6235.

Abstract

Radiation therapy is known to have a highly effective local and regional effect for cancer treatment; however, sporadic events of tumor regression in non-irradiated and irradiated fields have been observed over time, which is known as the "abscopal effect." In this report, we describe the case of a patient with a diagnosis of unresectable advanced gastric adenocarcinoma, who developed extensive retroperitoneal lymph node involvement and did not accept management with chemotherapy. Primary radiotherapy at the local level was offered to control hemostasis, reaching an important span of complete remission of the disease.

摘要

放射治疗在癌症治疗中具有高效的局部和区域治疗效果,这是众所周知的;然而,随着时间的推移,在未照射区域和照射区域均观察到了偶发的肿瘤消退事件,这被称为“远隔效应”。在本报告中,我们描述了一例被诊断为无法切除的晚期胃腺癌患者的病例,该患者出现广泛的腹膜后淋巴结转移,且不接受化疗。为控制止血,对其进行了局部的原发性放射治疗,使疾病达到了较长时间的完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc23/6935334/27ee76742b79/cureus-0011-00000006235-i01.jpg

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