Schmitz Christine, Hüttmann Andreas, Müller Stefan P, Hanoun Maher, Boellaard Ronald, Brinkmann Marcus, Jöckel Karl-Heinz, Dührsen Ulrich, Rekowski Jan
Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Data Brief. 2019 Dec 12;28:104976. doi: 10.1016/j.dib.2019.104976. eCollection 2020 Feb.
Total metabolic tumor volume (TMTV) was measured in 510 patients with DLBCL participating in the PETAL trial. The present data provide information about the prognostic impact of total metabolic tumor volume using the fixed standardized uptake value (SUV) instead of the relative SUV thresholding method. A Bland-Altman plot was created to compare both methods. For TMTV assessed by the SUV method a Cox regression was applied to determine its effect on time to progression, progression-free survival, and overall survival. Kaplan-Meier curves and corresponding hazard ratios were used to estimate the effect of TMTV alone or in combination with interim positron emission tomography response on patients' survival. The data relate to the research article entitled "Dynamic risk assessment based on positron emission tomography scanning in diffuse large B-cell lymphoma: post-hoc analysis from the PETAL trial" [1].
在参与PETAL试验的510例弥漫性大B细胞淋巴瘤（DLBCL）患者中测量了总代谢肿瘤体积（TMTV）。本数据提供了关于使用固定标准化摄取值（SUV）而非相对SUV阈值化方法的总代谢肿瘤体积的预后影响的信息。创建了Bland-Altman图以比较这两种方法。对于通过SUV方法评估的TMTV，应用Cox回归来确定其对进展时间、无进展生存期和总生存期的影响。使用Kaplan-Meier曲线和相应的风险比来估计TMTV单独或与中期正电子发射断层扫描反应相结合对患者生存的影响。这些数据与题为“基于正电子发射断层扫描的弥漫性大B细胞淋巴瘤动态风险评估：PETAL试验的事后分析”的研究文章相关[1]。
