Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Department of Newborn and Developmental Paediatrics, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
Am J Perinatol. 2021 Jul;38(8):796-803. doi: 10.1055/s-0039-3402718. Epub 2019 Dec 31.
To compare admission and emergency visits of late preterm (34-36 weeks) versus term infants (37-41 weeks) in the first 5 years.
This population-based cohort study included all singletons and twins born alive at 34 to 41 weeks' gestation registered in a health administrative database in Ontario, Canada, between April 1, 2002 and December 31, 2012. Admissions and emergency visits from initial postnatal discharge to 5 years were compared between late preterm and term infants adjusting for maternal and infant characteristics.
A total of 1,316,931 infants (75,364 late preterm infants) were included. Late preterm infants had more frequent admissions than term infants in the first 5 years in both singletons (adjusted incidence rate ratio [95% confidence interval] = 1.46 [1.42-1.49]) and twins (1.21 [1.11-1.31]). The difference in admissions between late preterm and term infants were smaller in twins than singletons and decreased with children's ages. Twins had less frequent admissions than singletons for late preterm infants, but not for term infants. The emergency visits were more frequent in late preterm than term infants in all the periods.
Admissions and emergency visits were more frequent in late preterm than term infants through the first 5 years. Admissions were less frequent in late preterm twins than singletons.
比较晚期早产儿（34-36 周）和足月儿（37-41 周）在出生后 5 年内的入院和急诊就诊情况。
这项基于人群的队列研究纳入了 2002 年 4 月 1 日至 2012 年 12 月 31 日期间在加拿大安大略省一个健康管理数据库中登记的所有活产单胎和双胎，胎龄为 34 至 41 周。通过调整母婴特征，比较晚期早产儿和足月儿在出生后首次 5 年内的入院和急诊就诊情况。
共有 1316931 名婴儿（75364 名晚期早产儿）被纳入研究。在单胎（校正发病率比[95%置信区间] = 1.46 [1.42-1.49]）和双胎（1.21 [1.11-1.31]）中，晚期早产儿在前 5 年的入院率均高于足月儿。晚期早产儿与足月儿的入院率差异在双胎中小于单胎，且随儿童年龄的增长而减小。与单胎相比，双胎的晚期早产儿入院率较低，但足月儿的入院率没有差异。在所有时期，晚期早产儿的急诊就诊率均高于足月儿。
在出生后 5 年内，晚期早产儿的入院和急诊就诊次数均多于足月儿。晚期早产儿双胎的入院率低于单胎。
