纤维肌痛对银屑病关节炎患者疲劳的影响：与对照组的比较。

The impact of the presence of fibromyalgia on fatigue in patients with psoriatic arthritis: comparison with controls.

机构信息

Department of Physical Medicine and Rehabilitation, Medical Faculty, Ondokuz Mayıs University, Samsun, Turkey.

Department of Physical Medicine and Rehabilitation, Division of Rheumatology, İstanbul Okmeydanı Research and Training Hospital, University of Health Sciences, İstanbul, Turkey.

出版信息

Adv Rheumatol. 2019 Dec 31;60(1):1. doi: 10.1186/s42358-019-0104-6.

DOI:10.1186/s42358-019-0104-6

PMID:31892345

Abstract

BACKGROUND

Coexisting fibromyalgia (FM) to psoriatic arthritis (PsA) has been identified and it has been associated with more severe symptoms, impaired function, and greater disability. It was aimed to explore the effect of the presence of FM on fatigue in patients with PsA comparing with controls.

METHODS

Fifty patients with PsA and 34 sex-age matched controls were enrolled. In patients; pain was assessed by Visual Analogue Scale, disease activity by DAS-28, enthesitis by The Leeds Enthesitis Index. Fatigue level of all participants was evaluated by Multidimensional Assessment of Fatigue. In all participants, FM was determined according to 2010 American College of Rheumatology criteria.

RESULTS

Seventeen patients with PsA (34%) and 4 controls (11.8%) were diagnosed with FM and all of them were women. There was significant difference between the patients and controls in terms of presence of FM (p < 0.05). Patients' fatigue scores were significantly higher than controls' (p = 0.001). There were significant differences between the PsA patients with and without FM with regard to gender, enthesitis, DAS-28 and pain scores (p < 0.05); fatigue scores (p < 0.001). The significant effect of the presence of FM on fatigue was found by univariate analysis of variance in patients (p < 0.001).

CONCLUSION

It was observed that FM presence and fatigue were more common in PsA patients than controls and comorbid FM had significant effect on fatigue in these patients. Physicians should be aware of the possibility of concomitant FM in patients with PsA.

摘要

背景

共存纤维肌痛（FM）和银屑病关节炎（PsA）已被确定，并且与更严重的症状、功能受损和更大的残疾有关。本研究旨在通过与对照组比较，探讨 FM 对 PsA 患者疲劳的影响。

方法

共纳入 50 例 PsA 患者和 34 名性别年龄匹配的对照者。在患者中，通过视觉模拟评分法评估疼痛，通过 DAS-28 评估疾病活动，通过利兹附着点指数评估附着点炎。通过多维疲劳评估评估所有参与者的疲劳水平。在所有参与者中，根据 2010 年美国风湿病学会标准确定 FM。

结果

17 例 PsA 患者（34%）和 4 名对照者（11.8%）被诊断为 FM，且均为女性。患者与对照组之间 FM 的存在存在显著差异（p<0.05）。患者的疲劳评分明显高于对照组（p=0.001）。在是否存在 FM 方面，PsA 患者在性别、附着点炎、DAS-28 和疼痛评分方面存在显著差异（p<0.05）；疲劳评分方面存在显著差异（p<0.001）。单因素方差分析显示，FM 的存在对患者的疲劳有显著影响（p<0.001）。