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菠萝蛋白酶与木瓜蛋白酶凝胶用于乳牙龋齿去除的比较

Bromelain vs Papain Gel for Caries Removal in Primary Teeth.

作者信息

Reddy Vamsi K, Nagar Priya, Reddy Swetha, Ragulakollu Rajesh, Tirupathi Sunny P, Ravi Ramakrishna, Purumadla Usha

机构信息

Department of Pedodontics and Preventive Dentistry, Malla Reddy Institute of Dental Sciences, Hyderabad, Telangana, India.

Department of Pedodontics and Preventive Dentistry, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.

出版信息

J Contemp Dent Pract. 2019 Nov 1;20(11):1345-1349.

Abstract

AIM

The aim of the study was to evaluate and compare bromelain with papain as the chemomechanical caries removal agent in relation to their efficacy.

MATERIALS AND METHODS

Thirty extracted primary molars with active carious lesion extending into dentin were selected. The samples were randomly divided into groups by sectioning the samples into two halves. Group I-cavity prepared using papain gel; group II-cavity prepared using bromelain gel. Time taken for caries removal in both the groups (I and II) was recorded with the help of a stopwatch. Following caries removal, the amount of remaining demineralized dentin was measured with the help of stereomicroscope and weld check (biological image analysis) software.

RESULTS

test is used to evaluate the significance of study parameters on continuous scale between two groups on metric parameters. The mean of residual carious dentin thickness obtained from the group II (bromelain) was 36.74 μm, which was much lower than that obtained from group I (papain) with a mean of 73.84 μm. The mean time taken in the group II (bromelain) was 335.30 seconds which was nearly equal to the mean time of group I (papain) of 352.33 seconds.

CONCLUSION

The amount of remaining demineralized dentin was found to be lower in bromelain group than the papain group and time taken for the carious dentin removal was almost found similar in both bromelain and papain groups. It may be concluded that bromelain was more effective in amount of caries removal than papain.

CLINICAL SIGNIFICANCE

Chemomechanical caries removal with the organic gels pose a great benefit as they are less invasive and has low side effects and cost-effective. How to cite this article: Reddy VK, Nagar P, Reddy S, Bromelain vs Papain Gel for Caries Removal in Primary Teeth. J Contemp Dent Pract 2019;20(11):1345-1349.

摘要

目的

本研究旨在评估和比较菠萝蛋白酶与木瓜蛋白酶作为化学机械性龋齿去除剂的疗效。

材料与方法

选取30颗有活性龋损且已累及牙本质的拔除乳牙。通过将样本切成两半,将其随机分组。第一组——使用木瓜蛋白酶凝胶制备窝洞;第二组——使用菠萝蛋白酶凝胶制备窝洞。借助秒表记录两组(第一组和第二组)去除龋齿所需的时间。去除龋齿后,借助体视显微镜和焊接检查(生物图像分析)软件测量剩余脱矿牙本质的量。

结果

该测试用于评估两组在连续尺度上关于度量参数的研究参数的显著性。从第二组(菠萝蛋白酶)获得的残余龋坏牙本质厚度平均值为36.74μm,远低于第一组(木瓜蛋白酶)获得的平均值73.84μm。第二组(菠萝蛋白酶)的平均用时为335.30秒,几乎等于第一组(木瓜蛋白酶)的平均用时352.33秒。

结论

发现菠萝蛋白酶组中剩余脱矿牙本质的量低于木瓜蛋白酶组,并且菠萝蛋白酶组和木瓜蛋白酶组去除龋坏牙本质所需的时间几乎相似。可以得出结论,菠萝蛋白酶在去除龋齿量方面比木瓜蛋白酶更有效。

临床意义

使用有机凝胶进行化学机械性龋齿去除具有很大益处,因为它们侵入性较小、副作用低且具有成本效益。如何引用本文:雷迪VK、纳加尔P、雷迪S,《菠萝蛋白酶与木瓜蛋白酶凝胶用于乳牙龋齿去除》。《当代牙科实践杂志》2019年;20(11):1345 - 1349。

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