Burt B A, Berman D S, Silverstone L M
Community Dent Oral Epidemiol. 1977 Jan;5(1):15-21. doi: 10.1111/j.1600-0528.1977.tb01612.x.
A clinical trial of one application of Nuva-Seal fissure sealant was conducted under School Dental Service conditions in a low-income area of London. The sealant was applied to one of a cariesfree pair of permanent teeth by schools' dentists, the other tooth being left as a control. One examiner, who did not apply the sealant, conducted examinations at baseline, after 6 months, and after 2 years. There were 118 children, initially aged 5-12, who remained in the trial after 2 years. The sealant was fully retained on 27.4 % of the teeth, partially retained on 40.6 %, and missing on 17.9 %. The remaining 14.1 % of teeth had been restored. There was no statistically significant difference between subjects who had less decay in sealed teeth and those who had less decay in control teeth. The sealant was 13.6 % effective (not significant, P less than 0.4) in preventing caries in sealed teeth. These results are less favorable than those in other trials reported. The potential role of fissure sealants in a School Dental Service is discussed.
在伦敦一个低收入地区的学校牙科服务条件下,开展了一项关于应用一次Nuva - Seal窝沟封闭剂的临床试验。学校牙医将封闭剂应用于一对无龋恒牙中的一颗,另一颗牙作为对照。一名未应用封闭剂的检查人员在基线、6个月后和2年后进行检查。最初年龄在5至12岁的118名儿童在2年后仍参与试验。封闭剂在27.4%的牙齿上完全保留,40.6%部分保留,17.9%缺失。其余14.1%的牙齿已进行修复。在封闭牙龋齿较少的受试者与对照牙龋齿较少的受试者之间,没有统计学上的显著差异。封闭剂在预防封闭牙龋齿方面的有效率为13.6%(不显著,P小于0.4)。这些结果不如其他报道的试验结果理想。本文讨论了窝沟封闭剂在学校牙科服务中的潜在作用。