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Epidiolex (Cannabidiol) Primer: Frequently Asked Questions for Patients and Caregivers.Epidiolex（大麻二酚）入门指南：患者及护理人员常见问题解答
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Cannabis and epilepsy.大麻与癫痫。
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Cannabidiol (Epidiolex) for epilepsy.用于癫痫的大麻二酚（艾必妥）
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Why marijuana is headed for the mainstream.为何大麻正走向主流。
Manag Care. 2018 Dec;27(12):31.
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Epidiolex as adjunct therapy for treatment of refractory epilepsy: a comprehensive review with a focus on adverse effects.Epidiolex作为难治性癫痫治疗的辅助疗法：一项聚焦于不良反应的综述
F1000Res. 2019 Feb 28;8. doi: 10.12688/f1000research.16515.1. eCollection 2019.
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Higher cannabidiol plasma levels are associated with better seizure response following treatment with a pharmaceutical grade cannabidiol.较高的大麻二酚血浆水平与经药物级大麻二酚治疗后的更好的癫痫发作反应相关。
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Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results.治疗抵抗性 Lennox-Gastaut 综合征或 Dravet 综合征患儿和成人使用大麻二酚的长期安全性和疗效：扩展使用项目结果。
Epilepsy Res. 2019 Aug;154:13-20. doi: 10.1016/j.eplepsyres.2019.03.015. Epub 2019 Mar 25.
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The use of cannabidiol for seizure management in patients with brain tumor-related epilepsy.大麻二酚在脑肿瘤相关性癫痫患者癫痫管理中的应用。
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Optimization of seizure prevention by cannabidiol (CBD).大麻二酚（CBD）预防癫痫发作的优化
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Mechanisms of Cell Death Induced by Cannabidiol Against Tumor Cells: A Review of Preclinical Studies.大麻二酚诱导肿瘤细胞死亡的机制：临床前研究综述
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Chemical analysis and concentrations of cannabidiol substances used for refractory epilepsy in Chilean patients. An underestimated worldwide risk.智利患者用于难治性癫痫的大麻二酚物质的化学分析及浓度。一种全球范围内被低估的风险。
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Discovery of Latent Cannabichromene Cyclase Activity in Marine Bacterial Flavoenzymes.海洋细菌黄素酶中潜伏大麻环素环化酶活性的发现。
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Unveiling the Potential of Cannabinoids in Multiple Sclerosis and the Dawn of Nano-Cannabinoid Medicine.揭示大麻素在多发性硬化症中的潜力与纳米大麻素医学的曙光。
Pharmaceutics. 2024 Feb 7;16(2):241. doi: 10.3390/pharmaceutics16020241.
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Long-term efficacy and adverse effects of cannabidiol in adjuvant treatment of drug-resistant epilepsy: a systematic review and meta-analysis.大麻二酚辅助治疗耐药性癫痫的长期疗效及不良反应：一项系统评价与荟萃分析
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本文引用的文献

1
Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.大麻二酚对 Lennox-Gastaut 综合征癫痫发作的影响。
N Engl J Med. 2018 May 17;378(20):1888-1897. doi: 10.1056/NEJMoa1714631.
2
Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial.Lennox-Gastaut 综合征相关癫痫患儿中使用大麻二酚治疗的随机、双盲、安慰剂对照 3 期临床试验（GWPCARE4）
Lancet. 2018 Mar 17;391(10125):1085-1096. doi: 10.1016/S0140-6736(18)30136-3. Epub 2018 Jan 26.
3
Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?大麻素用于癫痫治疗：终于有确凿证据了？
J Epilepsy Res. 2017 Dec 31;7(2):61-76. doi: 10.14581/jer.17012. eCollection 2017 Dec.
4
Cannabinoids in Pediatrics.儿科中的大麻素
J Pediatr Pharmacol Ther. 2017 May-Jun;22(3):176-185. doi: 10.5863/1551-6776-22.3.176.
5
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome.Dravet 综合征患者应用大麻二酚治疗耐药性癫痫发作的试验
N Engl J Med. 2017 May 25;376(21):2011-2020. doi: 10.1056/NEJMoa1611618.
6
Cannabinoids in treatment-resistant epilepsy: A review.大麻素类药物在难治性癫痫治疗中的应用综述
Epilepsy Behav. 2017 May;70(Pt B):341-348. doi: 10.1016/j.yebeh.2016.11.012. Epub 2017 Feb 8.

Epidiolex (Cannabidiol) Primer: Frequently Asked Questions for Patients and Caregivers.

作者信息

Abu-Sawwa Renad, Stehling Caitlin

出版信息

J Pediatr Pharmacol Ther. 2020 Jan-Feb;25(1):75-77. doi: 10.5863/1551-6776-25.1.75.

DOI:10.5863/1551-6776-25.1.75
PMID:31897080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6938286/
Abstract
摘要