Research Center for Biomedical and Health Science, Anhui Science and Technology University, Fengyang, 233100, China.
Institute of Medicine and Materials Applied Technologies, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu City, Shandong Province, 273165, People's Republic of China.
Mikrochim Acta. 2020 Jan 2;187(1):84. doi: 10.1007/s00604-019-4066-5.
A terbium(III)-functionalized zinc(II)-organic framework (Tb-MOF-Zn) is shown to be a viable fluorescent probe for phosphate. The organic ligands 4,4',4″-[((2,4,6-trimethylbenzene-1,3,5-triyl)tris(methylene))tris(oxy)]tribenzoic acid (HL) contains multiple carboxyl groups that can react with zinc(II) to yield tubular MOF-Zn. The MOF-Zn was further functionalized with Tb(III) to produce a lanthanide composite of type Tb-MOF-Zn which displays strong fluorescence with excitation/emission maxima at 285/544 nm. Fluorescence is quenched by phosphate because of the specific interaction with Tb(III) in Tb-MOF-Zn. The concentration of Tb-MOF-Zn, reaction time and pH value of the solution were optimized. Fluorescence drops linearly in the 0.01 to 200.0 μM phosphate concentration range, and the detection limit is 4.0 nM. The fluorescent probe was also used to prepare a microdot array on a glass slide for visual detection of phosphate under illumination with UV light. Graphical abstractA terbium(III) functionalized zinc(II)-organic framework was synthesized and used as fluorescent probe for determination of phosphate ions.
一种铽(III)功能化的锌(II)-有机骨架(Tb-MOF-Zn)被证明是一种可行的用于检测磷酸盐的荧光探针。有机配体 4,4',4″-[[((2,4,6-三甲苯-1,3,5-三基)三(亚甲基))三(氧基)]三苯甲酸(HL) 含有多个羧基，可与锌(II)反应生成管状 MOF-Zn。MOF-Zn 进一步用铽(III)功能化，生成 Tb-MOF-Zn 型的镧系复合材料，在 285/544nm 处显示出强荧光。由于 Tb-MOF-Zn 中 Tb(III)的特异性相互作用，荧光被磷酸盐猝灭。优化了 Tb-MOF-Zn 的浓度、反应时间和溶液的 pH 值。荧光在 0.01 到 200.0μM 的磷酸盐浓度范围内呈线性下降，检测限为 4.0nM。该荧光探针还用于在玻璃载玻片上制备微点阵列，用于在紫外光照射下对磷酸盐进行可视化检测。
