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癌症化疗患者恐惧复发的预测模型。

A predictive model of fear of cancer recurrence for patients undergoing chemotherapy.

机构信息

College of Nursing, Korea University, 145 Anam-ro, Seongbuk-Gu, 02841, Seoul, Republic of Korea.

出版信息

Support Care Cancer. 2020 Sep;28(9):4173-4181. doi: 10.1007/s00520-019-05245-7. Epub 2020 Jan 3.

DOI:10.1007/s00520-019-05245-7
PMID:31900611
Abstract

PURPOSE

A number of cancer patients experience fear of cancer recurrence (FCR), which affects their psychological adjustment. This study tested the hypothesized model of FCR to predict psychological adjustment in cancer patients undergoing chemotherapy.

METHODS

A total of 203 patients, who had been diagnosed with either breast cancer or colorectal cancer and were undergoing chemotherapy, were recruited from two university hospitals in Seoul, Korea. Data were collected using validated questionnaires and were analyzed using SPSS 24.0 and AMOS 25.0 program for structural equation modeling procedures.

RESULTS

The fit index of the hypothesized model was appropriate. Symptom distress, contextual factors, FCR, and illness representations had statistically significant direct, indirect, and total effects on psychological adjustment. These variables explained 76% of the total variance of the psychological adjustment in cancer patients undergoing chemotherapy. Fear of cancer recurrence was a mediating factor for the effects of symptom distress, contextual factors, and illness representation on psychological adjustment.

CONCLUSIONS

Based on these results, interventions aimed at reducing symptom distress and FCR, and improving social support, optimism, and illness representations, may be useful for the successful psychological adjustment of cancer patients undergoing chemotherapy.

摘要

目的

许多癌症患者经历癌症复发恐惧(FCR),这会影响他们的心理调整。本研究测试了 FCR 的假设模型,以预测接受化疗的癌症患者的心理调整。

方法

本研究共招募了 203 名来自韩国首尔两所大学附属医院的乳腺癌或结直肠癌患者,他们正在接受化疗。使用经过验证的问卷收集数据,并使用 SPSS 24.0 和 AMOS 25.0 程序进行结构方程模型分析。

结果

假设模型的拟合指数是适当的。症状困扰、情境因素、FCR 和疾病认知对接受化疗的癌症患者的心理调整有统计学上显著的直接、间接和总效应。这些变量解释了接受化疗的癌症患者心理调整总方差的 76%。FCR 是症状困扰、情境因素和疾病认知对心理调整影响的中介因素。

结论

基于这些结果,旨在减轻症状困扰和 FCR 以及改善社会支持、乐观和疾病认知的干预措施,可能对接受化疗的癌症患者的成功心理调整有用。

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