Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province/College of Chemistry & Chemical Engineering, China West Normal University, No. 1 Shi Da Road, Nanchong, 637009, China.
Chem Asian J. 2020 Mar 2;15(5):555-559. doi: 10.1002/asia.201901778. Epub 2020 Jan 28.
A photocatalytic E to Z isomerization of alkenes using an iridium photosensitizer under mild reaction conditions is disclosed. This method provides scalable and efficient access to Z-cinnamyl ether and allylic alcohol derivatives in high yields with excellent stereoselectivity. Importantly, this method also provides a powerful strategy for the selective synthesis of Z-magnolol and honokiol derivatives possessing potential biological activity.
公开了一种在温和反应条件下使用铱光引发剂进行烯烃的光催化 E 至 Z 异构化的方法。该方法以高产率和优异的立体选择性提供了可扩展且高效的合成 Z-肉桂基醚和烯丙基醇衍生物的途径。重要的是，该方法还为具有潜在生物活性的 Z-厚朴酚和厚朴酚衍生物的选择性合成提供了一种有力的策略。
