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后路内固定、减压及经椎弓根植骨治疗伴神经功能缺损的骨质疏松性爆裂骨折的临床影像学疗效

Clinico-Radiological Efficacy of Posterior Instrumentation, Decompression, and Transpedicular Bone Grafting in Osteoporotic Burst Fracture Associated with Neurological Deficit.

作者信息

Mehta Gaurav, Patel Ankit, Jain Sanyam, Merchant Zahir Abbas, Kundnani Vishal

机构信息

Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.

出版信息

Asian J Neurosurg. 2019 Nov 25;14(4):1207-1213. doi: 10.4103/ajns.AJNS_95_19. eCollection 2019 Oct-Dec.

Abstract

OBJECTIVE

The aim of this study is to evaluate clinico-radiological outcomes of posterior surgery (decompression + instrumentation + transpedicular bone graft) in osteoporotic burst fracture associated with neurological deficit [OFND].

MATERIALS AND METHODS

Forty patients with neurological deficit due to delayed osteoporotic vertebral collapse managed by posterior surgery (decompression + instrumentation + transpedicular bone graft) with minimum 2 years follow-up were included in the study. Approval from the Institutional Review Board was taken. Demographic data (age, sex, mode of injury, and the severity of osteoporosis); clinical parameters (Visual Analog Score [VAS], Oswestry Disability Index [ODI], Frankel grade), radiological parameters (local kyphosis), and surgical variables (blood loss, surgery duration, and intraoperative events) were recorded. Neurological worsening/improvement, complications, and implant failures were noted.

RESULTS

Significant improvement was noted in VAS (preoperative 8.20 ± 0.65/postoperative 4.1 ± 0.64) and ODI (preoperative 76.54 ± 6.96/postoperative 30.5 ± 6.56). Complete neurological recovery was noted in 37 patients (Frankel Grade E), three patients remained nonambulatory (Frankel Grade C). Significant improvement was noted in local kyphosis angle (preoperative = 21.80 ± 2.70; postoperative 11.40 ± 1.80), with 10% loss of correction (2.5 ± 0.90) at final follow-up. Symptomatic implant failure was noted in two patients and proximal junctional failure in one patient requiring an extension of fixation.

CONCLUSIONS

OFND can be managed with a single posterior-only surgery with significant improvement in neurology and functional scores of patients. Aggressive kyphosis correction is often not required and optimal correction of kyphosis is noticed due to prone-positioning alone. Transpedicular grafting is safe and simple alternative to cement augmentation or anterior surgery for collapsed vertebrae.

摘要

目的

本研究旨在评估后路手术(减压+内固定+经椎弓根植骨)治疗伴有神经功能缺损的骨质疏松性爆裂骨折[OFND]的临床和放射学结局。

材料与方法

本研究纳入40例因骨质疏松性椎体延迟塌陷导致神经功能缺损且接受后路手术(减压+内固定+经椎弓根植骨)并至少随访2年的患者。获得了机构审查委员会的批准。记录人口统计学数据(年龄、性别、损伤方式和骨质疏松严重程度);临床参数(视觉模拟评分[VAS]、Oswestry功能障碍指数[ODI]、Frankel分级)、放射学参数(局部后凸)和手术变量(失血量、手术时间和术中情况)。记录神经功能恶化/改善情况、并发症和内植物失败情况。

结果

VAS(术前8.20±0.65/术后4.1±0.64)和ODI(术前76.54±6.96/术后30.5±6.56)有显著改善。37例患者实现了神经功能完全恢复(Frankel E级),3例患者仍无法行走(Frankel C级)。局部后凸角有显著改善(术前=21.80±2.70;术后11.40±1.80),末次随访时矫正丢失10%(2.5±0.90)。2例患者出现有症状的内植物失败,1例患者出现近端交界性失败需要延长固定。

结论

OFND可通过单一后路手术治疗,患者的神经功能和功能评分有显著改善。通常不需要积极的后凸矫正,仅因俯卧位即可实现最佳的后凸矫正。经椎弓根植骨是椎体塌陷的骨水泥强化或前路手术的安全、简单替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e66/6896640/38b525ae12f8/AJNS-14-1207-g001.jpg

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