取卵后行胚胎移植时间对冻融周期临床结局的影响：一项回顾性队列研究。
Effect of the time for embryo transfer from oocyte retrieval on clinical outcomes in freeze-all cycles: a retrospective cohort study.
机构信息
Center for Reproductive Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Department of Clinical Laboratory Medicine, Guangdong Second Provincial General Hospital, Guangzhou, 510317, China.
出版信息
Arch Gynecol Obstet. 2020 Jan;301(1):303-308. doi: 10.1007/s00404-019-05405-4. Epub 2020 Jan 4.
PURPOSE
To identify the optimal time for the frozen embryo transfer (FET) after oocyte retrieval in freeze-all cycles.
METHODS
A retrospective analysis of 977 patients was performed. Implantation, clinical pregnancy and live birth rates were analyzed.
RESULTS
No significant difference was found between the first FET performed in the first menstrual cycle group and performed within the subsequent menstrual cycle group in terms of implantation, pregnancy and live birth rates. To rule out the effect of endometrial thickness, a hierarchical analysis was performed. There were no differences between groups for pregnancy, multiple pregnancy and live birth rates for all ranges of endometrial thickness.
CONCLUSIONS
The first FET should be performed once the endometrial thickness has been prepared well rather than delaying until the subsequent menstrual cycles.
目的
确定冻融胚胎移植（FET）的最佳时间在取卵后冷冻所有周期。
方法
对 977 例患者进行回顾性分析。分析胚胎着床率、临床妊娠率和活产率。
结果
在第一次月经周期组和随后月经周期组进行的第一次 FET 中，胚胎着床率、妊娠率和活产率无显著差异。为排除子宫内膜厚度的影响，进行了分层分析。在所有子宫内膜厚度范围内，各组妊娠率、多胎妊娠率和活产率差异均无统计学意义。
结论
一旦子宫内膜准备好，就应该进行第一次 FET，而不是延迟到随后的月经周期。
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