Epidemiology and Applied Research Branch, Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Reproductive Statistics Branch, National Center for Health Statistics, Division of Vital Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland.
JAMA Intern Med. 2020 Feb 1;180(2):274-280. doi: 10.1001/jamainternmed.2019.5727.
Pelvic examination is no longer recommended for asymptomatic, nonpregnant women and may cause harms such as false-positive test results, overdiagnosis, anxiety, and unnecessary costs. The bimanual pelvic examination (BPE) is an invasive and controversial examination component. Cervical cancer screening is not recommended for women younger than 21 years.
To estimate prevalence of potentially unnecessary BPE and Papanicolaou (Pap) tests performed among adolescent girls and women younger than 21 years (hereinafter referred to as young women) in the United States and to identify factors associated with receiving these examinations.
DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional analysis of the National Survey of Family Growth from September 2011 through September 2017 focused on a population-based sample of young women aged 15 to 20 years (n = 3410). The analysis used survey weights to estimate prevalence and the number of people represented in the US population. Data were analyzed from December 21, 2018, through September 3, 2019.
Receipt of a BPE or a Pap test in the last 12 months and the proportion of potentially unnecessary examinations and tests.
Responses from 3410 young women aged 15 to 20 years were included in the analysis with 6-year sampling weights applied. Among US young women aged 15 to 20 years represented during the 2011-2017 study period, 4.8% (95% CI, 3.9%-5.9%) were pregnant, 22.3% (95% CI, 20.1%-24.6%) had undergone STI testing, and 4.5% (95% CI, 3.6%-5.5%) received treatment or medication for an STI in the past 12 months (Table 1). Only 2.0% (95% CI, 1.4%-2.9%) reported using an IUD, and 33.5% (95% CI, 30.8%-36.4%) used at least 1 other type of hormonal contraception in the past 12 months. Among US young women aged 15 to 20 years who were surveyed in the years 2011 through 2017, approximately 2.6 million (22.9%; 95% CI, 20.7%-25.3%) reported having received a BPE in the last 12 months. Approximately half of these examinations (54.4%; 95% CI, 48.8%-59.9%) were potentially unnecessary, representing an estimated 1.4 million individuals. Receipt of a BPE was associated with having a Pap test (adjusted prevalence ratio [aPR], 7.12; 95% CI, 5.56-9.12), testing for sexually transmitted infections (aPR, 1.60; 95% CI, 1.34-1.90), and using hormonal contraception other than an intrauterine device (aPR, 1.31; 95% CI, 1.11-1.54). In addition, an estimated 2.2 million young women (19.2%; 95% CI, 17.2%-21.4%) reported having received a Pap test in the past 12 months, and 71.9% (95% CI, 66.0%-77.1%) of these tests were potentially unnecessary.
This analysis found that more than half of BPEs and almost three-quarters of Pap tests performed among young women aged 15 to 20 years during the years 2011 through 2017 were potentially unnecessary, exposing women to preventable harms. The results suggest that compliance with the current professional guidelines regarding the appropriate use of these examinations and tests may be lacking.
盆腔检查不再推荐用于无症状、非妊娠的女性,因为可能会导致假阳性结果、过度诊断、焦虑和不必要的费用。双合诊(BPE)是一种有创且有争议的检查项目。不建议 21 岁以下的女性进行宫颈癌筛查。
估计在美国,15 至 20 岁的少女和年轻女性(以下简称年轻女性)中,进行不必要的双合诊和巴氏涂片(Pap)检查的比例,并确定与接受这些检查相关的因素。
设计、地点和参与者:本研究采用 2011 年 9 月至 2017 年 9 月期间全国家庭增长调查的横断面分析,针对的是年龄在 15 至 20 岁的年轻女性人口。分析使用调查权重来估计流行率和在美国人口中的代表人数。数据于 2018 年 12 月 21 日至 2019 年 9 月 3 日进行分析。
在过去 12 个月内接受双合诊或巴氏涂片检查的比例,以及潜在不必要检查和测试的比例。
对 3410 名年龄在 15 至 20 岁的年轻女性的分析包括 6 年的抽样权重。在 2011 年至 2017 年研究期间代表的美国 15 至 20 岁的年轻女性中,4.8%(95%可信区间,3.9%-5.9%)怀孕,22.3%(95%可信区间,20.1%-24.6%)接受过性传播感染检测,4.5%(95%可信区间,3.6%-5.5%)在过去 12 个月内接受过性传播感染的治疗或药物治疗(表 1)。仅有 2.0%(95%可信区间,1.4%-2.9%)的女性报告使用宫内节育器,33.5%(95%可信区间,30.8%-36.4%)在过去 12 个月内使用了至少一种其他类型的激素避孕方法。在 2011 年至 2017 年接受调查的美国 15 至 20 岁的年轻女性中,大约有 260 万人(22.9%;95%可信区间,20.7%-25.3%)报告在过去 12 个月内接受过双合诊。其中约一半(54.4%;95%可信区间,48.8%-59.9%)检查可能是不必要的,估计有 140 万人。接受双合诊与接受巴氏涂片检查(调整后患病率比[aPR],7.12;95%可信区间,5.56-9.12)、性传播感染检测(aPR,1.60;95%可信区间,1.34-1.90)和使用除宫内节育器以外的激素避孕方法(aPR,1.31;95%可信区间,1.11-1.54)相关。此外,估计有 220 万年轻女性(19.2%;95%可信区间,17.2%-21.4%)报告在过去 12 个月内接受了巴氏涂片检查,其中 71.9%(95%可信区间,66.0%-77.1%)的检查可能是不必要的。
本分析发现,在 2011 年至 2017 年期间,15 至 20 岁的年轻女性中,超过一半的双合诊和近四分之三的巴氏涂片检查可能是不必要的,这使女性面临可预防的伤害。结果表明,目前对这些检查和测试的适当使用的专业指南可能没有得到遵守。