[与阿昔洛韦类似的化合物。III. 5'-脱氧核苷的无环类似物的合成]
[Compounds similar to acyclovir. III. Synthesis of acyclic analogs of 5'-deoxynucleosides].
作者信息
Smirnov I P, Kochetkova S V, Shchaveleva I L, Tsilevich T L, Gottikh B P
出版信息
Bioorg Khim. 1988 Jul;14(7):921-5.
PMID:3190776
Abstract
A convenient method has been proposed for the synthesis of 1,2-dihydroxy-4-oxahex-3-yl and 1-hydroxy-4-oxahex-3-yl derivatives of guanine, adenine, thymine and cytosine, acyclic nucleoside analogues lacking the 3'--4' bond.
摘要
已提出一种简便方法，用于合成鸟嘌呤、腺嘌呤、胸腺嘧啶和胞嘧啶的1,2 - 二羟基 - 4 - 氧杂己 - 3 - 基及1 - 羟基 - 4 - 氧杂己 - 3 - 基衍生物，即缺乏3' - 4'键的无环核苷类似物。
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