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胰腺和胃肠道黏膜中的血管活性肠肽（VIP）细胞。一项免疫组织化学和超微结构研究。

Vasoactive intestinal peptide (VIP) cells in the pancrease and gastro-intestinal mucosa. An immunohistochemical and ultrastructural study.

作者信息

Buffa R, Capella C, Solcia E, Frigerio B, Said S I

出版信息

Histochemistry. 1977 Jan 24;50(3):217-27. doi: 10.1007/BF00491069.

DOI:10.1007/BF00491069
PMID:319084
Abstract

Using antibodies against pure porcine VIP in immunoperoxidase and immunofluorescence tests, VIP-immunoreactive cells have been detected in the pancreas-especially in the islets-and gastrointestinal mucosa of the dog, guinea-pig and man. VIP immunoreactive cells were widely distributed in these tissues, never being numerous at any site. Some parallelism has been noted between such cells and ultrastructurally identified D1 cells fo the pancreas and gastrointestinal mucosa. The presence of VIP cells in normal pancreas may help explain the occurrence of pancreatic endocrine tumors producing VIP.

摘要

在免疫过氧化物酶和免疫荧光试验中，使用抗纯猪血管活性肠肽（VIP）的抗体，在狗、豚鼠和人的胰腺（尤其是胰岛）以及胃肠道黏膜中检测到了VIP免疫反应性细胞。VIP免疫反应性细胞广泛分布于这些组织中，在任何部位数量都不多。已注意到这些细胞与胰腺和胃肠道黏膜中经超微结构鉴定的D1细胞之间存在一定的相似性。正常胰腺中VIP细胞的存在可能有助于解释产生VIP的胰腺内分泌肿瘤的发生。

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Histochemistry. 1977 Jan 24;50(3):217-27. doi: 10.1007/BF00491069.
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Immunohistochemical localization of polypeptides in peripheral autonomic nerves using whole mount preparations.使用整装标本对外周自主神经中的多肽进行免疫组织化学定位。
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VIP innervation of the tongue in vertebrates.脊椎动物舌头的血管活性肠肽神经支配。
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Distribution of vasoactive intestinal polypeptide-like immunoreactivity in the mammalian heart. Interrelation with neurotensin- and substance P-like immunoreactive nerves.血管活性肠肽样免疫反应性物质在哺乳动物心脏中的分布。与神经降压素样和P物质样免疫反应性神经的相互关系。
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The interaction of vasoactive intestinal polypeptide (VIP), glucose and arginine on the secretion of insulin, glucagon and somatostatin in the perfused rat pancreas.血管活性肠肽（VIP）、葡萄糖和精氨酸对灌注大鼠胰腺中胰岛素、胰高血糖素和生长抑素分泌的相互作用。
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具有广泛生物活性的多肽：从小肠中分离得到。
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4
The ultrastructural basis for the identification of cell types in the pancreatic islets. II. Rabbit, dog and opossum.
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Isolation from porcine-intestinal wall of a vasoactive octacosapeptide related to secretin and to glucagon.从猪肠壁中分离出一种与促胰液素和胰高血糖素相关的血管活性二十八肽。
Eur J Biochem. 1972 Jul 13;28(2):199-204. doi: 10.1111/j.1432-1033.1972.tb01903.x.
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The pancreatic islet of infants with severe hypoglycemia.
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Fixation of ejaculated spermatozoa for electron microscopy.用于电子显微镜检查的射出精子的固定
Nature. 1967 Oct 14;216(5111):173-4. doi: 10.1038/216173a0.
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The endocrine cells of the pig gastrointestinal mucosa and pancreas.猪胃肠道黏膜和胰腺的内分泌细胞。
Arch Histol Jpn. 1972 Nov;35(1):1-29. doi: 10.1679/aohc1950.35.1.
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Cellular localization of a vasoactive intestinal peptide in the mammalian and avian gastrointestinal tract.血管活性肠肽在哺乳动物和鸟类胃肠道中的细胞定位。
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Gastroenterology. 1974 Oct;67(4):737-8.