Pereira Filipa, von Gunten Armin, Rosselet Amoussou Joëlle, De Giorgi Salamun Isabella, Martins Maria Manuela, Verloo Henk
School of Health Sciences, HES-SO Valais-Wallis, Sion, Switzerland.
Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal.
Patient Prefer Adherence. 2019 Dec 16;13:2137-2143. doi: 10.2147/PPA.S232575. eCollection 2019.
Ageing populations with multiple chronic conditions challenge low-, middle-, and high-income countries. Older adults frequently depend on complex medication regimens and polypharmacy, both of which can lead to potentially devastating and debilitating medication-related problems and to subsequent far-reaching public health, social, and economic effects. This perspectives article provides an overview of the current state of medication management, reflects on its relevance among polymedicated home-dwelling older adults living with multiple chronic conditions, and proposes patient-centered approaches for optimizing medication management and preventing medication-related problems.
老龄化人口伴有多种慢性病，这给低收入、中等收入和高收入国家带来了挑战。老年人常常依赖复杂的药物治疗方案和多种药物联用，而这两者都可能导致潜在的毁灭性和使人衰弱的药物相关问题，并进而产生深远的公共卫生、社会和经济影响。这篇观点文章概述了药物管理的现状，思考了其在患有多种慢性病的居家多药治疗老年人中的相关性，并提出了以患者为中心的方法来优化药物管理和预防药物相关问题。
