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眼睑双侧黑头粉刺痣:上睑下垂和睑外翻的罕见病因。

Bilateral nevus comedonicus of the eyelids: An unusual cause of ptosis and ectropion.

作者信息

Adam T, Hage R, Ahomadegbe C, Molinié V, Baubion E, Merle H

机构信息

Department of Ophthalmology, Centre Hospitalier Universitaire de Martinique, Martinique, French West Indies, France.

Department of Anatomy and Pathological Cytology Dermatology, Centre Hospitalier Universitaire de Martinique, Martinique, French West Indies, France.

出版信息

Am J Ophthalmol Case Rep. 2019 Dec 17;17:100579. doi: 10.1016/j.ajoc.2019.100579. eCollection 2020 Mar.

DOI:10.1016/j.ajoc.2019.100579
PMID:31909294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6938988/
Abstract

PURPOSE

Nevus comedonicus is a rare developmental abnormality of the infundibulum of the hair follicle.

OBSERVATION

We report here an unusual case of bilateral extensive nevus comedonicus of the eyelids complicated by bilateral ptosis and ectropion of the lower eyelids. Blepharoplasty was performed on both upper eyelids. Histopathological findings on skin biopsy typically show large, grouped, dilated follicular ostia filled with keratin.

CONCLUSIONS AND IMPORTANCE

This case is unusual as regards the late-onset (lesions first appeared at age 35) and location of the nevus comedonicus on both eyelids.

摘要

目的

粉刺痣是一种罕见的毛囊漏斗部发育异常。

观察

我们在此报告一例罕见的双侧广泛性眼睑粉刺痣病例,伴有双侧上睑下垂及下睑外翻。对双侧上睑进行了眼睑成形术。皮肤活检的组织病理学结果通常显示有大量、成簇、扩张的毛囊开口,内充满角蛋白。

结论及重要性

该病例在粉刺痣的迟发性(病变首次出现于35岁)及双侧眼睑的发病部位方面较为罕见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/0868f6d54d61/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/5fc79de43312/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/94786521172e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/0868f6d54d61/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/5fc79de43312/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/94786521172e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/686b/6938988/0868f6d54d61/gr3.jpg

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引用本文的文献

1
Bilateral nevus comedonicus of the eyelids: An unusual cause of ptosis and ectropion.眼睑双侧黑头粉刺痣:上睑下垂和睑外翻的罕见病因。
Am J Ophthalmol Case Rep. 2020 Aug 29;20:100907. doi: 10.1016/j.ajoc.2020.100907. eCollection 2020 Dec.

本文引用的文献

1
Bilateral nevus comedonicus of the eyelids associated with bladder cancer and successful treatment with topical tretinoin.眼睑双侧黑头粉刺痣伴膀胱癌及外用维甲酸成功治疗
Dermatol Ther. 2016 Nov;29(6):479-481. doi: 10.1111/dth.12385. Epub 2016 Aug 9.
2
Late-onset nevus comedonicus on both eyelids with hypothyroidism.双眼睑迟发性黑头粉刺痣伴甲状腺功能减退。
Cutis. 2014 Dec;94(6):E12-4.
3
Unilateral facial nevus comedonicus.单侧粉刺样痣
Indian Pediatr. 2013 Dec;50(12):1177-8. doi: 10.1007/s13312-013-0293-8.
4
Bilateral nevus comedonicus of the eyelids.双侧眼睑毛囊角化瘤。
Ophthalmic Plast Reconstr Surg. 2013 Jul-Aug;29(4):e95-8. doi: 10.1097/IOP.0b013e31827bdadb.
5
[Nevus comedonicus syndrome].[黑头粉刺痣综合征]
Ann Dermatol Venereol. 2007 Aug-Sep;134(8-9):663-6. doi: 10.1016/s0151-9638(07)91829-3.
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Extensive inflammatory nevus comedonicus involving half of the body.
Int J Dermatol. 2004 Jun;43(6):434-6. doi: 10.1111/j.1365-4632.2004.02188.x.
7
Posttraumatic nevus comedonicus.创伤后粉刺样痣
J Am Acad Dermatol. 1993 Feb;28(2 Pt 1):273-4. doi: 10.1016/s0190-9622(08)81155-3.