尼泊尔一家私立医院中，药剂师主导的针对哮喘患者吸入技术的干预措施以改善生活质量
Pharmacist Led Intervention on Inhalation Technique among Asthmatic Patients for Improving Quality of Life in a Private Hospital of Nepal.
作者信息
Yadav Anita, Thapa Parbati
机构信息
Pharmaceutical Sciences Program, School of Health and Allied Sciences, Pokhara University, Pokhara-30, Kaski, ZIP/Post code 33700, Nepal.
出版信息
Pulm Med. 2019 Nov 24;2019:8217901. doi: 10.1155/2019/8217901. eCollection 2019.
PURPOSE
Asthma is a chronic disease which cannot be cured but can be controlled. Although drug therapy is used to relieve and prevent symptoms of asthma and treat exacerbations, still a good asthma control and a better quality of life in many patients is suboptimal due to improper use of inhalation technique. Thus, this interventional study was conducted to evaluate the effect of a pharmacist intervention on asthma control, quality of life and inhaler technique in adult asthmatic patients.
PATIENTS AND METHODS
A total of 72 patients who met the inclusion criteria and agreed to give written consent were enrolled in the study. These patients were randomly divided into two groups i.e., test group (36) and control group (36) by simple block randomization technique. Test group were the interventional groups. Mini Asthma Quality of Life Questionnaire (AQLQ), Asthma Control Questionnaire (ACQ) and structured questionnaires were used to sort the information like quality of life, asthma control and demographic details. They were counselled by the pharmacist about the asthma management and proper use of inhalers. Out of 72 patients, only forty six patients came for follow up after one month. Data were entered and analyzed using Statistical Package for Social Sciences (SPSS) software version 20.
RESULTS
A significant change was observed in the mean score of quality of life ( = 0.001) in test group as well as control group, however change in the mean score of asthma control in the test group ( = 0.001) was more significant as compared to the control group ( = 0.099). Inhalation technique was found to be improved significantly after intervention among patients using the metered dose inhaler and dry powder inhaler. Majority of the patients were prescribed with Methylxanthines (24.5%) followed by combined Beta 2 agonists and Inhaled Corticosteroids (21.7%).
CONCLUSION
Pharmacist provided intervention improves the quality of life, asthma control and inhalation technique among asthmatic patients.
目的
哮喘是一种无法治愈但可得到控制的慢性疾病。尽管药物疗法用于缓解和预防哮喘症状并治疗急性发作，但由于吸入技术使用不当，许多患者的哮喘控制情况和生活质量仍未达到最佳状态。因此，开展了这项干预性研究，以评估药剂师干预对成年哮喘患者的哮喘控制、生活质量和吸入技术的影响。
患者与方法
共有72名符合纳入标准并同意签署书面知情同意书的患者参与了本研究。通过简单区组随机化技术将这些患者随机分为两组，即试验组（36例）和对照组（36例）。试验组为干预组。使用小型哮喘生活质量问卷（AQLQ）、哮喘控制问卷（ACQ）和结构化问卷来收集生活质量、哮喘控制情况及人口统计学细节等信息。药剂师就哮喘管理和吸入器正确使用方法对患者进行了指导。72名患者中，仅有46名患者在1个月后前来进行随访。使用社会科学统计软件包（SPSS）20.0版输入并分析数据。
结果
试验组和对照组的生活质量平均得分均出现了显著变化（P = 0.001），然而试验组哮喘控制平均得分的变化（P = 0.001）与对照组相比更为显著（P = 0.099）。在使用定量吸入器和干粉吸入器的患者中，干预后吸入技术有显著改善。大多数患者使用的药物为甲基黄嘌呤（24.5%），其次是β2激动剂和吸入性糖皮质激素联合使用（21.7%）。
结论
药剂师提供的干预措施可改善哮喘患者的生活质量、哮喘控制情况和吸入技术。
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