不吃早餐与超重和肥胖有关：系统评价和荟萃分析。
Skipping breakfast is associated with overweight and obesity: A systematic review and meta-analysis.
机构信息
Department of Diabetes and Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China; Luzhou Key Laboratory of Cardiovascular and Metabolic Diseases, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China; Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, Sichuan 646000, China.
Department of Diabetes and Endocrinology, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China; Luzhou Key Laboratory of Cardiovascular and Metabolic Diseases, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China; Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Southwest Medical University, Luzhou, Sichuan 646000, China.
出版信息
Obes Res Clin Pract. 2020 Jan-Feb;14(1):1-8. doi: 10.1016/j.orcp.2019.12.002. Epub 2020 Jan 7.
OBJECTIVE
In recent years, many original studies have shown that skipping breakfast has been associated with overweight and obesity; however, the results of different studies are inconsistent. Therefore, we conducted a systematic review and meta-analysis of observational studies to synthesize the associations between skipping breakfast and the risk of overweight/ obesity.
METHODS
We did a systematic search using Pubmed, and Ovid searched up to August 2019. Observational studies (cohort studies and cross-sectional studies) reporting adjusted Odds Ratio or Risk Ratio estimates for the association between breakfast skipping and overweight/obesity (including abdominal obesity). Summary odds ratio (or Risk Ratio) and 95% confidence intervals calculated with a random-effects model.
RESULTS
45 observational studies (36 cross-sectional studies and 9 cohort studies) were included in this meta-analysis. In cross-sectional studies, The ORs of low frequency breakfast intake per week versus high frequency were 1.48 (95% CI 1.40-1.57; I=54.0%; P=0.002) for overweight/obesity, 1.31 (95% CI 1.17-1.47; I=43.0%; P=0.15) for abdominal obesity. In cohort studies, The RR of low-frequency breakfast intake per week versus high frequency was 1.44 (95% CI 1.25-1.66; I=61%; P=0.009) for overweight/obesity.
CONCLUSIONS
This meta-analysis confirmed that skipping breakfast is associated with overweight/obesity, and skipping breakfast increases the risk of overweight/obesity. The results of cohort studies and cross-sectional studies are consistent. There is no significant difference in these results among different ages, gender, regions, and economic conditions.
目的
近年来，许多原始研究表明，不吃早餐与超重和肥胖有关；然而，不同研究的结果并不一致。因此，我们对观察性研究进行了系统回顾和荟萃分析，以综合分析不吃早餐与超重/肥胖风险之间的关系。
方法
我们使用 Pubmed 和 Ovid 进行了系统搜索，截至 2019 年 8 月进行了搜索。观察性研究（队列研究和横断面研究）报告了调整后的优势比或风险比估计值，用于评估不吃早餐与超重/肥胖（包括腹型肥胖）之间的关联。使用随机效应模型计算汇总优势比（或风险比）和 95%置信区间。
结果
本荟萃分析纳入了 45 项观察性研究（36 项横断面研究和 9 项队列研究）。在横断面研究中，每周低频率早餐摄入与高频率早餐摄入的比值比（OR）为 1.48（95%可信区间 1.40-1.57；I=54.0%；P=0.002），超重/肥胖的 OR 为 1.31（95%可信区间 1.17-1.47；I=43.0%；P=0.15），腹型肥胖的 OR 为 1.31（95%可信区间 1.17-1.47；I=43.0%；P=0.15）。在队列研究中，每周低频率早餐摄入与高频率早餐摄入的 RR 为 1.44（95%可信区间 1.25-1.66；I=61%；P=0.009），超重/肥胖的 RR 为 1.44（95%可信区间 1.25-1.66；I=61%；P=0.009）。
结论
本荟萃分析证实，不吃早餐与超重/肥胖有关，不吃早餐会增加超重/肥胖的风险。队列研究和横断面研究的结果一致。在不同的年龄、性别、地区和经济条件下，这些结果没有显著差异。
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