Sokolov S Ia, Belova L F, Baginskaia A I, Leskova T E, Gorodniuk T I
Farmakol Toksikol. 1988 Jul-Aug;51(4):93-6.
Various species of experimental animals were used for studying pharmacological properties of a new original antiviral (antiherpetic) agent alpizarin (2-beta-C-D-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone; with composition of C19H18O11) isolated from the aerial part of Hedysarum flaveacens Rgl. and Schmalh., Hedysarum alpinum L. It was found that in addition to the antiviral effect, alpizarin possesses also prominent cardiostimulant, capillary-strengthening, anti-inflammatory properties and enhances reparative processes in the gastric mucosa. The drug has no significant action on the central nervous system, the tone of peripheral vessels and intestinal smooth musculature and fails to influence carbohydrate metabolism and blood coagulation system.
使用了各种实验动物来研究从黄花岩黄芪（Hedysarum flaveacens Rgl. and Schmalh.）和高山岩黄芪（Hedysarum alpinum L.）地上部分分离出的一种新型原创抗病毒（抗疱疹）药物阿尔皮扎林（2-β-C-D-吡喃葡萄糖基-1,3,6,7-四羟基呫吨酮；化学式为C19H18O11）的药理特性。结果发现，除了抗病毒作用外，阿尔皮扎林还具有显著的心脏刺激、增强毛细血管、抗炎特性，并能促进胃黏膜的修复过程。该药物对中枢神经系统、外周血管张力和肠道平滑肌组织没有明显作用，也不影响碳水化合物代谢和血液凝固系统。
