Paşaoğlu A, Gök A, Patiroğlu T E
Department of Neurosurgery, Medical School of Erciyes University, Kayseri, Turkey.
Invest Radiol. 1988 Oct;23(10):762-6.
Myelography in dogs was performed with Pantopaque, iopamidol and iohexol. The effects of these agents were evaluated by histologic study of the brain, spinal cord, and meninges four months after the procedure. Retained Pantopaque was always accompanied by some degree of arachnoidal reaction, mild in the cervical cord segment and severe in the most caudal part of the cul-de-sac. No apparent protection against Pantopaque arachnoiditis was provided by either intrathecal or intramuscular methylprednisolone. We found no histologic evidence of arachnoiditis in animals examined with iopamidol and iohexol.
在犬类中使用泛影葡胺、碘帕醇和碘海醇进行脊髓造影。在操作四个月后，通过对脑、脊髓和脑膜进行组织学研究来评估这些药物的效果。残留的泛影葡胺总是伴有一定程度的蛛网膜反应，在颈髓节段较轻，在盲管最尾端部分较重。鞘内或肌肉注射甲基强的松龙均未对泛影葡胺蛛网膜炎提供明显的保护作用。在用碘帕醇和碘海醇检查的动物中，我们未发现蛛网膜炎的组织学证据。
