Jutesten Henrik, Lydrup Marie-Louise, Landberg Axel, Risberg Daniel, Ekberg Olle, Zackrisson Sophia, Buchwald Pamela
Department of Surgery, Lund University, Skåne University Hospital, Malmö, Sweden.
Department of Translational Medicine, Diagnostic Radiology, Lund University, Skåne University Hospital, Malmö, Sweden.
Acta Radiol Open. 2020 Jan 6;9(1):2058460119897358. doi: 10.1177/2058460119897358. eCollection 2020 Jan.
Permanent stoma (PS) is common following treatment of anastomotic leakage (AL) after anterior resection (AR) and ways of predicting successful treatment outcome are missing.
To explore radiological variables in rectal contrast studies in their relation to end-result of PS following treatment for AL after AR.
The Swedish Cancer Registry (SCRCR) was explored for AL cases after AR for rectal cancer in patients operated in the region of Skåne from 1 January 2001 to 31 December 2011. Among identified AL cases, patients subjected to radiological imaging consistent with AL were evaluated according to a predetermined set of radiological variables. Information of PS as the end-result after AL treatment were retrieved from medical records.
Thirty-two patients had radiological imaging available for analysis confirming AL after AR; PS rate after a median follow-up of 87 months (range = 21-165) after AR was 62%. Radiological findings compatible with abscess ( = 0.023) and a leak size ≤6 mm ( = 0.049) were significantly associated with PS.
In this limited explorative study, our findings suggest that abscess status and leak size could correspond to outcome of PS in treatment for AL after AR. Additional studies are warranted to further explore this subject.
永久性造口（PS）在前部切除术（AR）后吻合口漏（AL）的治疗中很常见，且缺乏预测治疗成功结果的方法。
探讨直肠造影研究中的放射学变量与AR后AL治疗后PS最终结果的关系。
对瑞典癌症登记处（SCRCR）进行探索，以查找2001年1月1日至2011年12月31日在斯科讷地区接受手术的直肠癌患者AR后发生AL的病例。在确定的AL病例中，根据一组预先确定的放射学变量对接受与AL一致的放射学成像的患者进行评估。从医疗记录中检索PS作为AL治疗后最终结果的信息。
32例患者有可用于分析的放射学成像，证实AR后发生AL；AR后中位随访87个月（范围=21-165）后的PS率为62%。与脓肿相符的放射学表现（=0.023）和漏口大小≤6mm（=0.049）与PS显著相关。
在这项有限的探索性研究中，我们的发现表明脓肿状态和漏口大小可能与AR后AL治疗中PS的结果相关。需要进一步的研究来进一步探索这个问题。
