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巴豆悬垂花籽油中泻下成分的提取、分离与鉴定。

The extraction, isolation and identification of the purgative component of Croton penduliflorus seed oil.

作者信息

Asuzu I U, Gray A I, Waterman P G

机构信息

Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka.

出版信息

J Ethnopharmacol. 1988 Jul-Aug;23(2-3):267-71. doi: 10.1016/0378-8741(88)90005-0.

DOI:10.1016/0378-8741(88)90005-0
PMID:3193789
Abstract

The purgative principles in Croton penduliflorus seed oil were isolated as white crystals by a bioassay-guided chromatographic separation process. The crystals were recovered in 7% w/w yield and identified (IR, 1H-NMR, GC-MS) as a mixture of palmitic, stearic and arachidic acids in approximately equimolar concentration.

摘要

通过生物活性导向的色谱分离法,从巴豆种子油中分离出具有泻下作用的成分,得到白色晶体。晶体的得率为7%(重量/重量),经鉴定(红外光谱、氢核磁共振谱、气相色谱-质谱联用)为棕榈酸、硬脂酸和花生酸的混合物,其浓度大致相等。

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