Torres Maria Conceição M, Assunção João Carlos, Santiago Gilvandete Maria P, Andrade-Neto Manoel, Silveira Edilberto R, Costa-Lotufo Leticia V, Bezerra Daniel P, Marinho Filho José Delano B, Viana Francisco Arnaldo, Pessoa Otília Deusdênia L
Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Chem Biodivers. 2008 Dec;5(12):2724-8. doi: 10.1002/cbdv.200890227.
The chemical composition of the leaf essential oil of Croton regelianus collected from wild plants growing in two different sites at Ceará State (Brazil) was analyzed by GC/MS and GC-FID. Twenty monoterpenoids, representing more than 96% of the chemical composition of the oils, were identified and quantified. The oils showed similar chemical composition but considerable variation in the levels of each constituent. Ascaridole (33.9-17.0%), p-cymene (22.3-21.6%), and camphor (13.0-3.1%) were the predominant constituents. The monoterpene ascaridole was isolated and characterized by spectroscopic data. The essential oils and the isolated compounds were tested against Aedes aegypti and Artemia sp. larvae, and the root knot nematode Meloidogyne incognita. The bioassay results show that the essential oil of C. regelianus and ascaridole were moderately active against the M. incognita, but strongly effective against both A. aegypti and Artemia sp. larvae.
采用气相色谱/质谱联用仪（GC/MS）和气相色谱-氢火焰离子化检测器（GC-FID），对采自巴西塞阿拉州两个不同地点野生植物的雷氏巴豆叶精油的化学成分进行了分析。共鉴定并定量了20种单萜类化合物，其含量占精油化学成分的96%以上。这些精油化学成分相似，但各成分含量存在显著差异。主要成分是蛔蒿素（33.9 - 17.0%）、对伞花烃（22.3 - 21.6%）和樟脑（13.0 - 3.1%）。通过光谱数据分离并鉴定了单萜蛔蒿素。对所得精油和分离出的化合物进行了抗埃及伊蚊和卤虫幼虫以及根结线虫南方根结线虫的测试。生物测定结果表明，雷氏巴豆精油和蛔蒿素对南方根结线虫有中等活性，但对埃及伊蚊和卤虫幼虫均有强效作用。
