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基础神经泌尿学

Basic neurourology.

作者信息

Kim Kwang Taek, Chang Hyun-Kyung, Kim Chang-Hee, Chung Kyung Jin, Brown Suzana, Kim Su Jin, Kim Khae-Hawn

机构信息

Department of Urology, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.

Department of Technology and Society, The State University of New York (SUNY) in Korea, Incheon, Korea.

出版信息

J Exerc Rehabil. 2019 Dec 31;15(6):747-750. doi: 10.12965/jer.1938744.372. eCollection 2019 Dec.

DOI:10.12965/jer.1938744.372
PMID:31938693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6944880/
Abstract

The integrated coordination of the components of the lower urinary tract is mediated by the complex neuromodulatory system of the brain, spinal cord, and peripheral ganglia. Therefore, the central nervous system plays a crucial role in the storage and output of urine. The purpose of this review article is to present the key aspects of the structure of the peripheral nervous system and central nervous system related to the lower urinary tract, as well as the mechanisms of action and the control system of innervation regulating the storage and output of urine. Furthermore, this article discusses the clinical significance and directions of neurourological research, concluding with the suggestions for with the neurourological research prospects.

摘要

下尿路各组成部分的整合协调是由大脑、脊髓和外周神经节的复杂神经调节系统介导的。因此,中枢神经系统在尿液储存和排出中起着关键作用。这篇综述文章的目的是介绍与下尿路相关的外周神经系统和中枢神经系统的结构关键方面,以及调节尿液储存和排出的神经支配的作用机制和控制系统。此外,本文还讨论了神经泌尿学研究的临床意义和方向,最后给出了神经泌尿学研究前景的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a1/6944880/d706c6f24447/jer-15-6-747f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a1/6944880/d706c6f24447/jer-15-6-747f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50a1/6944880/d706c6f24447/jer-15-6-747f1.jpg

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本文引用的文献

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Treadmill Exercise Improves Motor Function by Suppressing Purkinje Cell Loss in Parkinson Disease Rats.跑步机运动通过抑制帕金森病大鼠浦肯野细胞丢失来改善运动功能。
Int Neurourol J. 2018 Oct;22(Suppl 3):S147-155. doi: 10.5213/inj.1836226.113. Epub 2018 Oct 31.
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Electrical Activity of the Bladder Is Attenuated by Intravesical Inhibition of P2X2/3 Receptors During Micturition in Female Rats.在雌性大鼠排尿过程中,膀胱内P2X2/3受体的抑制作用会减弱膀胱的电活动。
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Afferent Pathway-Mediated Effect of α1 Adrenergic Antagonist, Tamsulosin, on the Neurogenic Bladder After Spinal Cord Injury.
神经泌尿学研究的未来方向
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脊髓损伤后α1肾上腺素能拮抗剂坦索罗辛经传入通路介导对神经源性膀胱的作用
Int Neurourol J. 2017 Sep;21(3):178-188. doi: 10.5213/inj.1734984.492. Epub 2017 Sep 12.
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Expected Next-Generation Drugs.
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J Neurophysiol. 2009 Nov;102(5):2719-30. doi: 10.1152/jn.00700.2009. Epub 2009 Sep 9.
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