Dong Zhengya, Delacour Claire, Mc Carogher Keiran, Udepurkar Aniket Pradip, Kuhn Simon
Department of Chemical Engineering, KU Leuven, 3001 Leuven, Belgium.
Materials (Basel). 2020 Jan 11;13(2):344. doi: 10.3390/ma13020344.
Ultrasonic small scale flow reactors have found increasing popularity among researchers as they serve as a very useful platform for studying and controlling ultrasound mechanisms and effects. This has led to the use of these reactors for not only research purposes, but also various applications in biological, pharmaceutical and chemical processes mostly on laboratory and, in some cases, pilot scale. This review summarizes the state of the art of ultrasonic flow reactors and provides a guideline towards their design, characterization and application. Particular examples for ultrasound enhanced multiphase processes, spanning from immiscible fluid-fluid to fluid-solid systems, are provided. To conclude, challenges such as reactor efficiency and scalability are addressed.
超声波小型流动反应器在研究人员中越来越受欢迎，因为它们是研究和控制超声机制及效应的非常有用的平台。这不仅使得这些反应器被用于研究目的，还被用于生物、制药和化学过程中的各种应用，大多是在实验室规模，在某些情况下是中试规模。本综述总结了超声波流动反应器的技术现状，并为其设计、表征和应用提供了指导方针。还提供了超声强化多相过程的具体实例，范围从不互溶的液-液到液-固系统。最后，讨论了诸如反应器效率和可扩展性等挑战。
