Nabeya Daijiro, Kinjo Takeshi, Parrott Gretchen Lynn, Nakachi Sawako, Yamashiro Tomoko, Ikemiyagi Nanae, Arakaki Wakako, Masuzaki Hiroaki, Fujita Jiro
Department of Infectious, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Japan.
Division of Endocrinology, Diabetes and Metabolism, Hematology and Rheumatology, Graduate School of Medicine, University of the Ryukyus, Japan.
Intern Med. 2020;59(2):247-252. doi: 10.2169/internalmedicine.3117-19. Epub 2020 Jan 15.
Studies reporting chest images of respiratory syncytial virus (RSV)-induced lower respiratory tract infection (LRTI) in an outbreak setting and their relationship to the clinical manifestation are limited. During a genetically confirmed RSV outbreak, eight patients underwent both chest X-ray and computed tomography (CT). Among these, 5 cases had newly appearing abnormalities on CT, although chest X-ray was able to detect abnormalities in only 2 cases (40%). Although bronchial wall thickening was common, other findings and their distribution were variable, even in an outbreak setting. All patients with both a history of anticancer chemotherapy against hematological cancer and lower respiratory symptoms, such as wheezing, sputum, and hypoxemia, had abnormalities on CT, suggesting that these two factors might be important for predicting the existence of LRTI in RSV-infected patients.
关于呼吸道合胞病毒（RSV）引起的下呼吸道感染（LRTI）在暴发环境中的胸部影像及其与临床表现关系的研究有限。在一次经基因确认的RSV暴发期间，8例患者接受了胸部X线和计算机断层扫描（CT）检查。其中，5例CT有新出现的异常，而胸部X线仅能检测到2例异常（40%）。尽管支气管壁增厚很常见，但即使在暴发环境中，其他表现及其分布也存在差异。所有有血液系统癌症抗癌化疗史且有喘息、咳痰和低氧血症等下呼吸道症状的患者CT均有异常，提示这两个因素可能对预测RSV感染患者是否存在LRTI很重要。
