Alcalde A I, Ilundáin A
Departamento Biomedicina, Facultad de Veterinaria, Zaragoza, Spain.
Rev Esp Fisiol. 1988 Jun;44(2):147-50.
The effect of BaCl2 on galactose transport across isolated rat small intestine has been investigated. The addition of 5 mM BaCl2 or theophylline (3 mM) to the bathing solutions increased cell water free sugar accumulation and decreased mucosal to serosal sugar fluxes. However the effects of BaCl2 were smaller than those induced by theophylline. Removal of Ca2+ from the bathing solutions did not modify the response to BaCl2, though the response to theophylline was partially reduced. In the presence of 0.1 mM trifluoperazine, both theophylline and BaCl2 were without effect on sugar transport. These findings are discussed in terms of an effect of Ba2+ on intestinal smooth muscle tone.
研究了氯化钡对半乳糖跨分离大鼠小肠转运的影响。向浴液中添加5 mM氯化钡或茶碱（3 mM）可增加细胞内游离糖的积累，并减少黏膜到浆膜的糖通量。然而，氯化钡的作用小于茶碱所诱导的作用。从浴液中去除钙离子并不会改变对氯化钡的反应，尽管对茶碱的反应会部分降低。在存在0.1 mM三氟拉嗪的情况下，茶碱和氯化钡对糖转运均无影响。根据钡离子对肠道平滑肌张力的作用对这些发现进行了讨论。
