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可穿戴式人体实验室:在可穿戴设备中结合生化和数字标记物的传感

Wearable Lab on Body: Combining Sensing of Biochemical and Digital Markers in a Wearable Device.

作者信息

Pataranutaporn Pat, Jain Abhinandan, Johnson Casey M, Shah Pratik, Maes Pattie

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:3327-3332. doi: 10.1109/EMBC.2019.8857479.

Abstract

Wearables are being widely researched for monitoring individual's health and wellbeing. Current generation wearable devices sense an individual's physiological data such as heart rate, respiration, electrodermal activity, and EEG, but lack in sensing their biological counterparts, which drive the majority of individual's physiological signals. On the other hand, biosensors for detecting biochemical markers are currently limited to one-time use, are non-continuous and don't provide flexibility in choosing which biomarker they sense. We present "wearable lab on body", a platform for active continuous monitoring of human biomarkers from the biological fluid. Our platform contains both digital sensors such as IMU for activity recognition, as well as an automated system for continuous sampling of biomarkers from saliva by leveraging already existing paper-based biochemical sensors. The platform could aid with longitudinal studies of biomarkers and early diagnosis of diseases.

摘要

可穿戴设备正在被广泛研究用于监测个人的健康和福祉。当前一代的可穿戴设备能够感知个人的生理数据,如心率、呼吸、皮肤电活动和脑电图,但缺乏对驱动大多数生理信号的生物对应物的感知。另一方面,用于检测生化标志物的生物传感器目前仅限于一次性使用,不连续且在选择要检测的生物标志物方面缺乏灵活性。我们提出了“身体上的可穿戴实验室”,这是一个用于从生物流体中主动连续监测人类生物标志物的平台。我们的平台既包含用于活动识别的数字传感器,如惯性测量单元(IMU),也包含一个通过利用现有的基于纸张的生化传感器对唾液中的生物标志物进行连续采样的自动化系统。该平台有助于生物标志物的纵向研究和疾病的早期诊断。

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