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对比机器人辅助远端胃癌根治术与传统腹腔镜手术的临床疗效:倾向评分匹配分析

Comparison of surgical outcomes between integrated robotic and conventional laparoscopic surgery for distal gastrectomy: a propensity score matching analysis.

机构信息

Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

Department of Surgery, Ajou University School of Medicine, Suwon, Korea.

出版信息

Sci Rep. 2020 Jan 16;10(1):485. doi: 10.1038/s41598-020-57413-z.

DOI:10.1038/s41598-020-57413-z
PMID:31949219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6965606/
Abstract

This study was aimed to compare the surgical outcomes between conventional laparoscopic distal gastrectomy (CLDG) and integrated robotic distal gastrectomy (IRDG) which used both Single-Site platform and fluorescence image-guided surgery technique simultaneously. Retrospective data of 56 patients who underwent IRDG and 152 patients who underwent CLDG were analyzed. Propensity score matching analysis was performed to control selection bias using age, sex, American Society of Anesthesiologists score, and body mass index. Fifty-one patients were selected for each group. Surgical success was defined as the absence of open conversion, readmission, major complications, positive resection margin, and inadequate lymph node retrieval (<16). Patients characteristics and surgical outcomes of IRDG group were comparable to those of CLDG group, except longer operation time (159.5 vs. 131.7 min; P < 0.001), less blood loss (30.7 vs. 73.3 mL; P = 0.004), higher number of retrieved lymph nodes (LNs) (50.4 vs. 41.9 LNs; P = 0.025), and lower readmission rate (2.0 vs. 15.7%; P = 0.031). Surgical success rate was higher in IRDG group compared to CLDG group (98.0 vs. 82.4%; P = 0.008). In conclusion, this study found that IRDG provides the benefits of higher number of retrieved LNs, less blood loss, and lower readmission rate compared with CLDG in patients with early gastric cancer.

摘要

本研究旨在比较传统腹腔镜远端胃切除术(CLDG)和集成机器人远端胃切除术(IRDG)的手术结果,后者同时使用单部位平台和荧光图像引导手术技术。分析了 56 例行 IRDG 患者和 152 例行 CLDG 患者的回顾性数据。采用年龄、性别、美国麻醉医师协会评分和体重指数进行倾向评分匹配分析,以控制选择偏倚。每组选择 51 例患者。手术成功定义为无开放转换、再入院、主要并发症、阳性切缘和淋巴结采集不足(<16)。IRDG 组的患者特征和手术结果与 CLDG 组相当,除了手术时间较长(159.5 分钟比 131.7 分钟;P<0.001)、出血量较少(30.7 毫升比 73.3 毫升;P=0.004)、淋巴结采集数较多(50.4 个比 41.9 个淋巴结;P=0.025)和再入院率较低(2.0%比 15.7%;P=0.031)。与 CLDG 组相比,IRDG 组的手术成功率更高(98.0%比 82.4%;P=0.008)。总之,本研究发现,与 CLDG 相比,IRDG 可为早期胃癌患者提供更多淋巴结采集、更少出血和更低再入院率的优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/cf0b2ffe91d7/41598_2020_57413_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/a444ef216038/41598_2020_57413_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/bae2f0d535fd/41598_2020_57413_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/2c56bd9ae8a6/41598_2020_57413_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/cf0b2ffe91d7/41598_2020_57413_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/a444ef216038/41598_2020_57413_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/bae2f0d535fd/41598_2020_57413_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/2c56bd9ae8a6/41598_2020_57413_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c5/6965606/cf0b2ffe91d7/41598_2020_57413_Fig4_HTML.jpg

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