新型二羟丙茶碱衍生物4-苄基羟基苯甲酸[2-羟基-3-（茶碱-7-醇）]丙酯的降血脂作用
[Hypolipidemic effect of the new diprophylline derivative, [2-hydroxy-3-(theophylline-7-ol] propyl ester of 4-benzylhydroxybenzoic acid].
作者信息
Ryzhenkov V E, Chistiakova A M, Wójcicki J, Samochowiec L, Daday R
出版信息
Vopr Med Khim. 1988 Jul-Aug;34(4):109-12.
PMID:3195124
Abstract
A new derivative of diprophylline--[2-hydroxy-3(theophylline-7-ol)] propyl ester 4-benzyloxybenzoic acid was shown to decrease the content of cholesterol and of atherogenic lipoproteins in blood serum of hyperlipidemic guinea pigs. In blood serum of rabbits the new substance studied decreased cholesterol, free fatty acids and malonic dialdehyde concentrations.
摘要
二羟丙茶碱的一种新衍生物——4-苄氧基苯甲酸[2-羟基-3-(茶碱-7-醇)]丙酯，被证明可降低高脂血症豚鼠血清中的胆固醇和致动脉粥样硬化脂蛋白含量。在所研究的新物质作用下，兔血清中的胆固醇、游离脂肪酸和丙二醛浓度降低。
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