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[产前缺氧对不同年龄大鼠脑和血液中高肌肽水平的影响]

[Effect of antenatal hypoxia on homocarnosine levels in the brain and blood of rats of various ages].

作者信息

Bondarenko T I, Kondrashova I N

出版信息

Vopr Med Khim. 1988 Jul-Aug;34(4):24-6.

PMID:3195129
Abstract

Content of homocarnosine was studied in brain and blood of 14, 30 and 70 days old rats, mothers of which were subjected to hypoxia, corresponding to the height 9,000 m within 1 hr, during 2 week pregnancy. In 14 days old animals content of homocarnosine was increased by 43% in brain and 2-fold in blood, in 30 days old animals it was decreased by 13% in brain and increased 5-fold in blood after the antenatal hypoxia as compared with controls. Content of homocarnosine was similar to control values in brain and blood of 70 days old rats with antenatal hypoxia.

摘要

研究了14日龄、30日龄和70日龄大鼠大脑和血液中的高肌肽含量,这些大鼠的母亲在怀孕第2周时经历了相当于海拔9000米高度的1小时缺氧。与对照组相比,14日龄动物大脑中高肌肽含量增加43%,血液中增加1倍;30日龄动物产前缺氧后大脑中高肌肽含量降低13%,血液中增加5倍。产前缺氧的70日龄大鼠大脑和血液中的高肌肽含量与对照组值相似。

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