[Change in the free amino acid concentration of the developing brain under the influence of antenatal hypoxia].

Concentration of free amino acids was studied in various parts of brain (hemisphere, brain stem) of 14- and 30-days old rats with antenatal hypoxia. In hemispheres of 14-days old rats concentrations of 5 amino acids were altered, in the brain stem content of 3 amino acids was altered. In the pool of free amino acids of the 30-days old gats content of 7 amino acids was altered in hemispheres and content of 9 amino acids - in the brain stem. More rapid accumulation of cystathionine in hemispheres and of glycine in the brain stem was observed in animals with antenatal hypoxia. In these conditions accumulation of glutamic acid in hemispheres and of taurine - in the brain stem was retarded as compared with control animals.