Krichevskaia A A, Bondarenko T I, Makletsova M G, Lobova E F
Vopr Med Khim. 1985 Jan-Feb;31(1):74-6.
Content of homocarnosine was studied in rat brain departments and blood after hypoxia (9,000 m, 60 min) and hyperoxia (0.3 mPa of oxygen, 60 min) following the hypoxia. In hypoxia content of homocarnosine was unaltered in brain hemispheres and medulla oblongata, it was increased by 41% in midbrain and cerebellum and by 80% in blood. Simultaneous effect of hypoxia and hyperbaric oxygenation decreased the homocarnosine content in brain hemispheres by 22%, in midbrain and diencephalon by 61%, in medulla oblongata by 34%, in cerebellum by 66% and in blood by 39%. Thus, therapeutic doses of hyperbaric oxygenation did not normalize the homocarnosine content in brain of animals with hypoxia.
研究了缺氧（9000米，60分钟）及随后的高氧（0.3兆帕氧气，60分钟）后大鼠脑部各区域及血液中高肌肽的含量。缺氧时，大脑半球和延髓中高肌肽的含量未改变，中脑和小脑增加了41%，血液中增加了80%。缺氧与高压氧合同时作用使大脑半球中高肌肽含量降低22%，中脑和间脑降低61%，延髓降低34%，小脑降低66%，血液中降低39%。因此，治疗剂量的高压氧合未能使缺氧动物大脑中的高肌肽含量恢复正常。
